Glycosylase

Novel, inactive photocaged derivative of raseglurant which can be uncaged with violet light. Shows light-dependent analgesic activity in vivo.

Novel DREADD agonist with high affinity and potency for hM3Dq and hM4Di. Active in vivo. Freebase.

Novel DREADD agonist with high affinity and potency for hM3Dq and hM4Di. Active in vivo. Water soluble.

Novel DREADD agonist with high affinity and potency for hM3Dq and hM4Di. Active in vivo. Freebase.

Novel DREADD agonist with high affinity and potency for hM3Dq and hM4Di. Active in vivo. Water soluble.

Jumonji histone demethylase inhibitor

Downstream Hedgehog signaling pathway inhibitor. Alcohol dehydrogenase 7 inhibitor.

Potent, selective H₄ receptor silent antagonist

Potent, selective, non-competitive mGlu₁ antagonist

Potent, selective BET bromodomain inhibitor. Cell permeable.