Histone deacetylase (HDAC)

Histone acetylation is a key epigenetic process - it is upregulated during memory formation but downregulated in numerous neurodegenerative diseases (eg. Alzheimer's disease and Huntington's disease). There are 18 Histone Deacetylase (HDAC) enzymes that are classified into two groups, the histone deacetylase family and the sirtuin family. The histone deacetylase family is further divided into classes I, II and IV. HDAC inhibitors are a class of compounds that increase acetylation of lysine residues on histone proteins as well as other, nonhistone, proteins by inhibiting the activity of these HDAC enzymes. Researchers can save up to 50% on HDAC inhibitors from Hello Bio - they are up to half the price of other suppliers.

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  1. Description:

    Potent, selective CDK1, CDK2, CDK5 and CDK9 inhibitor

    Purity:

    >95%

    Pack:
    5mg
    Price:
    $357
    Qty:
  2. Perlapine (HB4889)

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    Description:

    Effective agonist for muscarinic-based DREADDs in vitro and in vivo. Non-CNO chemogenetic actuator

    Purity:

    >98%

    Pack:
    1mg
    Price:
    $34
    Qty:
    Pack:
    10mg
    Price:
    $133
    Qty:
    Pack:
    50mg
    Price:
    $551
    Qty:
  3. Description:

    Effective agonist for muscarinic-based DREADDs in vitro and in vivo. Non-CNO chemogenetic actuator. Water soluble.

    Purity:

    >98%

    Pack:
    1mg
    Price:
    $45
    Qty:
    Pack:
    10mg
    Price:
    $137
    Qty:
    Pack:
    50mg
    Price:
    $575
    Qty:
  4. PETCM (HB1292)

    Description:

    Caspase-3 activator

    Purity:

    >99%

    Pack:
    50mg
    Price:
    $208
    Qty:
    Pack:
    250mg
    Price:
    $842
    Qty:
  5. Pack:
    10mg
    Price:
    $230
    Qty:
    Pack:
    50mg
    Price:
    $771
    Qty:
  6. Pack:
    10mg
    Price:
    $178
    Qty:
    Pack:
    50mg
    Price:
    $721
    Qty:
  7. Pack:
    10mg
    Price:
    $215
    Qty:
    Pack:
    50mg
    Price:
    $847
    Qty:
  8. Pack:
    300 tests
    Price:
    $224
    Qty:
    Pack:
    100μg
    Price:
    $233
    Qty:
  9. Description:

    GSK-3β inhibitor

    Purity:

    >97%

    Pack:
    1mg
    Price:
    $185
    Qty:
  10. Pack:
    10mg
    Price:
    $241
    Qty:
    Pack:
    50mg
    Price:
    $962
    Qty:
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