Histone deacetylase (HDAC)

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Histone acetylation is a key epigenetic process - it is upregulated during memory formation but downregulated in numerous neurodegenerative diseases (eg. Alzheimer's disease and Huntington's disease). There are 18 Histone Deacetylase (HDAC) enzymes that are classified into two groups, the histone deacetylase family and the sirtuin family. The histone deacetylase family is further divided into classes I, II and IV. HDAC inhibitors are a class of compounds that increase acetylation of lysine residues on histone proteins as well as other, nonhistone, proteins by inhibiting the activity of these HDAC enzymes. Researchers can save up to 50% on HDAC inhibitors from Hello Bio - they are up to half the price of other suppliers.

Items 71-80 of 717

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  1. Description:

    Hedgehog signaling inhibitor. Δ,7-dehydrocholesterol reductase inhibitor.

    Purity:

    >99%

    Pack:
    10mg
    Price:
    $169
    Qty:
  2. Description:

    DNA methyltransferase inhibitor

    Purity:

    >99%

    Pack:
    10mg
    Price:
    $116
    Qty:
    Pack:
    50mg
    Price:
    $460
    Qty:
  3. 5-Azacytidine (HB1374)

    Description:

    DNA methyltransferase inhibitor. Improves stem cell reprogramming efficiency and induces differentiation of MSCs into cardiomyocytes.

    Purity:

    >98%

    Pack:
    50mg
    Price:
    $69
    Qty:
    Pack:
    250mg
    Price:
    $95
    Qty:
  4. Description:

    Potent and ATP-competitive GSK-3β inhibitor

    Purity:

    >98%

    Pack:
    5mg
    Price:
    $482
    Qty:
  5. Pack:
    10mg
    Price:
    $32
    Qty:
    Pack:
    50mg
    Price:
    $94
    Qty:
    Pack:
    250mg
    Price:
    $372
    Qty:
  6. Bafilomycin A1 (HB1125)

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    Description:

    Highly potent, selective V-ATPase inhibitor. Autophagy inhibitor.

    Purity:

    >98%

    Pack:
    10μg
    Price:
    $110
    Qty:
    Pack:
    100μg
    Price:
    $303
    Qty:
  7. Bafilomycin C1 (HB3792)

    Description:

    Specific vacuolar-type H+-ATPase inhibitor

    Purity:

    >98%

    Pack:
    1mg
    Price:
    $189
    Qty:
  8. Pack:
    10mg
    Price:
    $175
    Qty:
    Pack:
    25mg
    Price:
    $347
    Qty:
    Pack:
    100mg
    Price:
    $1,102
    Qty:
  9. BAY 11-7082 (HB3793)

    Description:

    IκBα kinase and NF-κB inhibitor.

    Purity:

    >99%

    Pack:
    50mg
    Price:
    $410
    Qty:
  10. Pack:
    5mg
    Price:
    $97
    Qty:
    Pack:
    10mg
    Price:
    $141
    Qty:
    Pack:
    50mg
    Price:
    $565
    Qty:
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