Histone deacetylase (HDAC)

Histone acetylation is a key epigenetic process - it is upregulated during memory formation but downregulated in numerous neurodegenerative diseases (eg. Alzheimer's disease and Huntington's disease). There are 18 Histone Deacetylase (HDAC) enzymes that are classified into two groups, the histone deacetylase family and the sirtuin family. The histone deacetylase family is further divided into classes I, II and IV. HDAC inhibitors are a class of compounds that increase acetylation of lysine residues on histone proteins as well as other, nonhistone, proteins by inhibiting the activity of these HDAC enzymes. Researchers can save up to 50% on HDAC inhibitors from Hello Bio - they are up to half the price of other suppliers.

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  1. Spironolactone (HB2799)

    Description:

    Mineralocorticoid and androgen receptor antagonist

    Purity:

    >98%

    Pack:
    50mg
    Price:
    $55
    Qty:
  2. Splitomicin (HB4091)

    Description:

    Potent,selective, cell permeable yeast NAD+-dependent HDAC Sir2p inhibitor

    Purity:

    >98%

    Pack:
    25mg
    Price:
    $370
    Qty:
  3. Pack:
    10mg
    Price:
    $249
    Qty:
    Pack:
    50mg
    Price:
    $978
    Qty:
  4. Pack:
    10mg
    Price:
    $107
    Free trial
    Qty:
    Pack:
    50mg
    Price:
    $410
    Qty:
    Pack:
    10mM (add 1ml water)
    Price:
    $69
    Qty:
  5. Stattic (HB1437)

    Description:

    Selective STAT3 inhibitor

    Purity:

    >99%

    Pack:
    5mg
    Price:
    $65
    Qty:
    Pack:
    25mg
    Price:
    $262
    Qty:
  6. Stauprimide (HB3011)

    Description:

    NME2 nuclear translocation inhibitor. Primes ESCs for differentiation.

    Purity:

    >98%

    Pack:
    100μg
    Price:
    $194
    Qty:
  7. Pack:
    1mg
    Price:
    $420
    Qty:
  8. Stigmasterol (HB4095)

    Description:

    Phytosterol with anticancer and many other biological actions. Farnesoid X receptor antagonist.

    Purity:

    >95%

    Pack:
    5g
    Price:
    $249
    Qty:
  9. Pack:
    10mg
    Price:
    $238
    Qty:
    Pack:
    50mg
    Price:
    $896
    Qty:
  10. Streptochlorin (HB4096)

    Description:

    TNFα-induced NF-κB activation inhibitor.

    Purity:

    >95%

    Pack:
    1mg
    Price:
    $408
    Qty:
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