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Images Staurosporine product vial image | Hello Bio
Staurosporine product vial image | Hello Bio Biological Data Biological description Potent and non-specific protein kinase inhibitor (IC50 values are 3, 7, 6 and 20 nM at PKC, PKA, p60v-src tyrosine protein kinase and CAMKII respectively). Cell permeable. Induces apoptosis.
Solubility & Handling Storage instructions +4°C
Solubility overview Soluble in DMSO (25mg/ml) or DMF (25mg/ml)
Important This product is for RESEARCH USE ONLY and is not intended for therapeutic or diagnostic use. Not for human or veterinary use.
Chemical Data Chemical name Antibiotic AM-2282
Chemical structure
Molecular Formula C28 H26 N4 O3
SMILES CC12C(C(CC(O1)N3C4=CC=CC=C4C5=C6C(=C7C8=CC=CC=C8N2C7=C53)CNC6=O)NC)OC
InChiKey HKSZLNNOFSGOKW-FYTWVXJKSA-N
References for Staurosporine References are publications that support the biological activity of the product
Staurosporine: an effective inhibitor for Ca2+/calmodulin-dependent protein kinase II. Yanagihara N et al (1991) J Neurochem 56(1) : 294-8. Staurosporine, K-252 and UCN-01: potent but nonspecific inhibitors of protein kinases. Rüegg UT et al (1989) Trends Pharmacol Sci 10(6) : 218-20. Staurosporine, a potent inhibitor of phospholipid/Ca++dependent protein kinase. Tamaoki T et al (1986) Biochem Biophys Res Commun 135(2) : 397-402.
Publications
These publications cite the use of Staurosporine purchased from Hello Bio:
Spider venoms and chronic pain–developing novel pharmacological tools from the spider venoms to target P2X4 in microglia Bibic et al (2020) UEA : Thesis
Potent, non-specific protein kinase inhibitor. Apoptosis inducer.
![Staurosporine [62996-74-1] Chemical Structure](https://hellobio.com/media/catalog/product//h/b/hb0590.png "Staurosporine [62996-74-1]")
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