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Staurosporine

(HB0590)
Publications (1)
Technical documents: SDS Datasheet
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Product overview

Name Staurosporine
Alternative names AM-2282, STS
Purity >98%
Description Potent, non-specific protein kinase inhibitor. Apoptosis inducer.
Biological Data Solubility & Handling Chemical Data Related Areas Calculators Technical guides (1) Reviews Publications (1) References (3) Frequently bought together
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Staurosporine product vial image | Hello Bio
Staurosporine product vial image | Hello Bio

Staurosporine product vial image | Hello Bio

Staurosporine product vial image | Hello Bio

Biological Data

Biological description Potent and non-specific protein kinase inhibitor (IC50 values are 3, 7, 6 and 20 nM at PKC, PKA, p60v-src tyrosine protein kinase and CAMKII respectively). Cell permeable. Induces apoptosis.

Solubility & Handling

Solubility overview Soluble in DMSO (25mg/ml) or DMF (25mg/ml)
Storage instructions +4°C
Storage of solutions Prepare and use solutions on the same day if possible. Store solutions at -20°C for up to one month if storage is required. Equilibrate to RT and ensure the solution is precipitate free before use.
Shipping Conditions Stable for ambient temperature shipping. Follow storage instructions on receipt.
Important This product is for RESEARCH USE ONLY and is not intended for therapeutic or diagnostic use. Not for human or veterinary use.

Calculators

Molarity

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Dilution

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Chemical Data

Purity >98%
Chemical name Antibiotic AM-2282
Molecular Weight 466.53
Chemical structure Staurosporine [62996-74-1] Chemical Structure
Molecular Formula C28H26N4O3
CAS Number 62996-74-1
PubChem identifier 44259
SMILES CC12C(C(CC(O1)N3C4=CC=CC=C4C5=C6C(=C7C8=CC=CC=C8N2C7=C53)CNC6=O)NC)OC
InChiKey HKSZLNNOFSGOKW-FYTWVXJKSA-N

References for Staurosporine

References are publications that support the biological activity of the product

  • Staurosporine: an effective inhibitor for Ca2+/calmodulin-dependent protein kinase II.

    Yanagihara N et al (1991) J Neurochem 56(1) : 294-8.
    Read more (PubMedID: 1846174)

  • Staurosporine, K-252 and UCN-01: potent but nonspecific inhibitors of protein kinases.

    Rüegg UT et al (1989) Trends Pharmacol Sci 10(6) : 218-20.
    Read more (PubMedID: 2672462)

  • Staurosporine, a potent inhibitor of phospholipid/Ca++dependent protein kinase.

    Tamaoki T et al (1986) Biochem Biophys Res Commun 135(2) : 397-402.
    Read more (PubMedID: 3457562)

3 Item(s)

Publications
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These publications cite the use of Staurosporine purchased from Hello Bio:

  • Spider venoms and chronic pain–developing novel pharmacological tools from the spider venoms to target P2X4 in microglia

    Bibic et al (2020) UEA : Thesis

1 Item

Grouped product items
Order: HB0590
Pack PriceQty
1mg
$420
Potent, non-specific protein kinase inhibitor. Apoptosis inducer.
Shipping Info

Standard: $35

Hazardous: $35

Shipped on ice: $35

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