Histone deacetylase (HDAC)

Histone acetylation is a key epigenetic process - it is upregulated during memory formation but downregulated in numerous neurodegenerative diseases (eg. Alzheimer's disease and Huntington's disease). There are 18 Histone Deacetylase (HDAC) enzymes that are classified into two groups, the histone deacetylase family and the sirtuin family. The histone deacetylase family is further divided into classes I, II and IV. HDAC inhibitors are a class of compounds that increase acetylation of lysine residues on histone proteins as well as other, nonhistone, proteins by inhibiting the activity of these HDAC enzymes. Researchers can save up to 50% on HDAC inhibitors from Hello Bio - they are up to half the price of other suppliers.

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  1. Quinolactacin A (HB4047)

    Description:

    Acetylcholinesterase (AChE) inhibitor

    Purity:

    >95%

    Pack:
    5mg
    Price:
    $496
    Qty:
  2. Q-VD-OPh (HB4048)

    Description:

    Cell permeable, irreversible and non-toxic pan-caspase inhibitor

    Purity:

    >95%

    Pack:
    1mg
    Price:
    $241
    Qty:
    Pack:
    5mg
    Price:
    $985
    Qty:
  3. Pack:
    100mg
    Price:
    $103
    Qty:
    Pack:
    100mM (add 1ml water)
    Price:
    $65
    Qty:
  4. Pack:
    50mg
    Price:
    $112
    Qty:
    Pack:
    100mM (add 1ml water)
    Price:
    $91
    Qty:
  5. Description:

    Potent, selective, competitive H2 receptor antagonist

    Purity:

    >99%

    Pack:
    50mg
    Price:
    $71
    Qty:
  6. Rapamycin (HB2779)

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    Description:

    mTOR inhibitor and potent immunosuppressant. Also used in inducible gene editing methods (e.g. CRISPR/Cas9) and promotes hPSC differentiation.

    Purity:

    >98%

    Pack:
    1mg
    Price:
    $146
    Free trial
    Qty:
    Pack:
    5mg
    Price:
    $247
    Qty:
  7. Description:

    Selective, irreversible MAO-B inhibitor

    Purity:

    >99%

    Pack:
    50mg
    Price:
    $71
    Qty:
  8. Pack:
    10mg
    Price:
    $133
    Qty:
    Pack:
    50mg
    Price:
    $542
    Qty:
  9. Rebeccamycin (HB4052)

    Description:

    Weak topoisomerase I inhibitor. Shows no activity against protein kninases.

    Purity:

    >98%

    Pack:
    1mg
    Price:
    $479
    Qty:
  10. Pack:
    250mg
    Price:
    $783
    Qty:
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