Histone deacetylase (HDAC)

Histone acetylation is a key epigenetic process - it is upregulated during memory formation but downregulated in numerous neurodegenerative diseases (eg. Alzheimer's disease and Huntington's disease). There are 18 Histone Deacetylase (HDAC) enzymes that are classified into two groups, the histone deacetylase family and the sirtuin family. The histone deacetylase family is further divided into classes I, II and IV. HDAC inhibitors are a class of compounds that increase acetylation of lysine residues on histone proteins as well as other, nonhistone, proteins by inhibiting the activity of these HDAC enzymes. Researchers can save up to 50% on HDAC inhibitors from Hello Bio - they are up to half the price of other suppliers.

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  1. Cytostatin (HB3864)

    Description:

    Potent, selective PP2A inhibitor

    Purity:

    >75%

    Pack:
    250μg
    Price:
    $357
    Qty:
  2. Pack:
    10mg
    Price:
    $215
    Qty:
    Pack:
    50mg
    Price:
    $836
    Qty:
  3. Pack:
    100mg
    Price:
    $151
    Qty:
    Pack:
    500mg
    Price:
    $609
    Qty:
  4. Pack:
    50mg
    Price:
    $133
    Qty:
  5. Pack:
    5mg
    Price:
    $80
    Qty:
    Pack:
    25mg
    Price:
    $320
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    Pack:
    10mg
    Price:
    $76
    Qty:
  6. Description:

    Selective serotonin reuptake inhibitor (SSRI)

    Purity:

    >99%

    Pack:
    10mg
    Price:
    $119
    Qty:
    Pack:
    50mg
    Price:
    $426
    Qty:
  7. DAPT (HB3345)

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    Description:

    γ-secretase inhibitor and classical notch inhibitor. Induces neuronal differentiation. 3D Growth matrix component and used in cerebral organoid differentiation media.

    Purity:

    >98%

    Pack:
    5mg
    Price:
    $103
    Free trial
    Qty:
    Pack:
    10mg
    Price:
    $175
    Qty:
    Pack:
    25mg
    Price:
    $436
    Qty:
    Pack:
    50mg
    Price:
    $733
    Qty:
    Pack:
    10mM (1mL in DMSO)
    Price:
    $114
    Qty:
  8. Pack:
    1mg
    Price:
    Qty:
    Pack:
    5mg
    Price:
    $153
    Qty:
    Pack:
    10mg
    Price:
    $193
    Qty:
    Pack:
    50mg
    Price:
    $806
    Qty:
  9. Description:

    Histone methyltransferase inhibitor. Enhances Oct4 expression in chemically-induced pluripotent stem cells.

    Purity:

    >98%

    Pack:
    500μg
    Price:
    $123
    Qty:
    Pack:
    1mg
    Price:
    $180
    Qty:
    Pack:
    5mg
    Price:
    $812
    Qty:
  10. Description:

    Cholesterol biosynthesis inhibitor

    Purity:

    >98%

    Pack:
    5mg
    Price:
    $454
    Qty:
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