Histone deacetylase (HDAC)

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Histone acetylation is a key epigenetic process - it is upregulated during memory formation but downregulated in numerous neurodegenerative diseases (eg. Alzheimer's disease and Huntington's disease). There are 18 Histone Deacetylase (HDAC) enzymes that are classified into two groups, the histone deacetylase family and the sirtuin family. The histone deacetylase family is further divided into classes I, II and IV. HDAC inhibitors are a class of compounds that increase acetylation of lysine residues on histone proteins as well as other, nonhistone, proteins by inhibiting the activity of these HDAC enzymes. Researchers can save up to 50% on HDAC inhibitors from Hello Bio - they are up to half the price of other suppliers.

Items 191-200 of 718

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    10mg
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    $213
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    50mg
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    $827
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    100mg
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    50mg
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    25mg
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    10mg
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    $74
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  5. Description:

    Selective serotonin reuptake inhibitor (SSRI)

    Purity:

    >99%

    Pack:
    10mg
    Price:
    $116
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    50mg
    Price:
    $414
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  6. DAPT (HB3345)

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    Description:

    γ-secretase inhibitor and classical notch inhibitor. Induces neuronal differentiation. 3D Growth matrix component and used in cerebral organoid differentiation media.

    Purity:

    >98%

    Pack:
    5mg
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    10mg
    Price:
    $168
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    25mg
    Price:
    $418
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    50mg
    Price:
    $703
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    Pack:
    10mM (1mL in DMSO)
    Price:
    $109
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    1mg
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    5mg
    Price:
    $147
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    10mg
    Price:
    $185
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    50mg
    Price:
    $773
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  8. Description:

    Histone methyltransferase inhibitor. Enhances Oct4 expression in chemically-induced pluripotent stem cells.

    Purity:

    >98%

    Pack:
    500μg
    Price:
    $118
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    Pack:
    1mg
    Price:
    $173
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    Pack:
    5mg
    Price:
    $777
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  9. Description:

    Cholesterol biosynthesis inhibitor

    Purity:

    >98%

    Pack:
    5mg
    Price:
    $441
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  10. Description:

    TGF-β signaling inhibitor

    Purity:

    >95%

    Pack:
    5mg
    Price:
    $502
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