Selective inhibitor of the stress-induced Protein Phosphatase 1 Regulatory Subunit 15A (PP1R15A). Guanabenz derivative. Does not bind the related PP1R15B. Protects cells from protein misfolding stress and prevents protein-misfolding diseases such as Charcot-Marie-Tooth 1B and amyotrophic lateral sclerosis in vivo.
Solubility & Handling
Solubility overview
Soluble in DMSO (100 mM)
Storage instructions
+4°C
Storage of solutions
Prepare and use solutions on the same day if possible. Store solutions at -20°C for up to one month if storage is required. Equilibrate to RT and ensure the solution is precipitate free before use.
Shipping Conditions
Stable for ambient temperature shipping. Follow storage instructions on receipt.
Important
This product is for RESEARCH USE ONLY and is not intended for therapeutic or diagnostic use. Not for human or veterinary use.
![Sephin 1 [951441-04-6] Chemical Structure](https://cdn.hellobio.com/media/catalog/product//h/b/hb4296.png "Sephin 1 [951441-04-6]")
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