Selective inhibitor of the stress-induced Protein Phosphatase 1 Regulatory Subunit 15A (PP1R15A). Guanabenz derivative. Does not bind the related PP1R15B. Protects cells from protein misfolding stress and prevents protein-misfolding diseases such as Charcot-Marie-Tooth 1B and amyotrophic lateral sclerosis in vivo.
Solubility & Handling
Storage instructions
+4°C
Solubility overview
Soluble in DMSO (100 mM)
Important
This product is for RESEARCH USE ONLY and is not intended for therapeutic or diagnostic use. Not for human or veterinary use.