Histone deacetylase (HDAC)

Histone acetylation is a key epigenetic process - it is upregulated during memory formation but downregulated in numerous neurodegenerative diseases (eg. Alzheimer's disease and Huntington's disease). There are 18 Histone Deacetylase (HDAC) enzymes that are classified into two groups, the histone deacetylase family and the sirtuin family. The histone deacetylase family is further divided into classes I, II and IV. HDAC inhibitors are a class of compounds that increase acetylation of lysine residues on histone proteins as well as other, nonhistone, proteins by inhibiting the activity of these HDAC enzymes. Researchers can save up to 50% on HDAC inhibitors from Hello Bio - they are up to half the price of other suppliers.

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  1. AACOCF3 (HB2354)

    Description:

    Selective cPLA2 inhibitor

    Pack:
    50mg
    Price:
    $616
    Qty:
  2. 17-AAG (HB3599)

    Description:

    Selective Hsp90 inhibitor. Also protects neuroprogenitor cells against apoptosis.

    Purity:

    >98%

    Pack:
    1mg
    Price:
    $135
    Qty:
  3. Description:

    Phytohormone and endogenous lanthionine synthetase C-like 2 (LANCL2) ligand

    Purity:

    >99%

    Pack:
    10mg
    Price:
    $143
    Free trial
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    Pack:
    50mg
    Price:
    $626
    Qty:
  4. Description:

    Potent dopamine D4 receptor partial agonist

    Purity:

    >99%

    Pack:
    50mg
    Price:
    $644
    Qty:
  5. Pack:
    100mg
    Price:
    $240
    Qty:
  6. Pack:
    1g
    Price:
    $136
    Qty:
    Pack:
    5g
    Price:
    $495
    Qty:
  7. Pack:
    10mg
    Price:
    $358
    Qty:
  8. Actinomycin D (HB1477)

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    Description:

    RNA polymerase inhibitor. Apoptosis inducer.

    Purity:

    >98%

    Pack:
    10mg
    Price:
    $129
    Qty:
    Pack:
    5mg
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    Pack:
    100mg
    Price:
    $925
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    Pack:
    25mg
    Price:
    $243
    Qty:
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