Histone deacetylase (HDAC)

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Histone acetylation is a key epigenetic process - it is upregulated during memory formation but downregulated in numerous neurodegenerative diseases (eg. Alzheimer's disease and Huntington's disease). There are 18 Histone Deacetylase (HDAC) enzymes that are classified into two groups, the histone deacetylase family and the sirtuin family. The histone deacetylase family is further divided into classes I, II and IV. HDAC inhibitors are a class of compounds that increase acetylation of lysine residues on histone proteins as well as other, nonhistone, proteins by inhibiting the activity of these HDAC enzymes. Researchers can save up to 50% on HDAC inhibitors from Hello Bio - they are up to half the price of other suppliers.

Items 1-10 of 440

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  1. 1233B (HB3710)

    Description:

    Antibiotic

    Purity:

    >95%

    Pack:
    1mg
    Price:
    $196
    Qty:
  2. A11 (HB9579)

    Description:

    ANXA1 (Annexin A1) derived peptide. Blocks ANXA1-EphA2 interaction.

    Pack:
    1mg
    Price:
    $286
    Qty:
  3. Pack:
    10mg
    Price:
    $200
    Qty:
    Pack:
    50mg
    Price:
    $807
    Qty:
  4. A83-01 (HB3218)

    2  Reviews
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    Description:

    Selective TGF-βRI (ALK5), ALK4 and ALK7 inhibitor. Maintains human hiPSC self renewal, 3D growth matrix component and promotes long-term organoid growth. Aids fibroblast to NSC/cardiomyocyte reprogramming.

    Purity:

    >98%

    Pack:
    5mg
    Price:
    $88
    Qty:
    Pack:
    25mg
    Price:
    $297
    Qty:
  5. 17-AAG (HB3599)

    Description:

    Selective Hsp90 inhibitor. Also protects neuroprogenitor cells against apoptosis.

    Purity:

    >98%

    Pack:
    1mg
    Price:
    $133
    Qty:
  6. Description:

    Phytohormone and endogenous lanthionine synthetase C-like 2 (LANCL2) ligand

    Purity:

    >99%

    Pack:
    10mg
    Price:
    $139
    Qty:
    Pack:
    50mg
    Price:
    $608
    Qty:
  7. Description:

    Fluorogenic tri-peptide substrate. Useful for measuring trypsin-like 20S proteasome peptidase activity.

    Purity:

    >97%

    Pack:
    5mg
    Price:
    $333
    Qty:
  8. Acetomycin (HB3734)

    Description:

    Antibiotic with antibacterial, antifungal and antiprotozoal activity

    Purity:

    >98%

    Pack:
    5mg
    Price:
    $398
    Qty:
  9. 1  Review
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    Description:

    Artificial cerebrospinal fluid (aCSF)

    Pack:
    25mL
    Price:
    $103
    Qty:
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