Histone deacetylase (HDAC)

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Histone acetylation is a key epigenetic process - it is upregulated during memory formation but downregulated in numerous neurodegenerative diseases (eg. Alzheimer's disease and Huntington's disease). There are 18 Histone Deacetylase (HDAC) enzymes that are classified into two groups, the histone deacetylase family and the sirtuin family. The histone deacetylase family is further divided into classes I, II and IV. HDAC inhibitors are a class of compounds that increase acetylation of lysine residues on histone proteins as well as other, nonhistone, proteins by inhibiting the activity of these HDAC enzymes. Researchers can save up to 50% on HDAC inhibitors from Hello Bio - they are up to half the price of other suppliers.

Items 1-10 of 1319

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  1. 1233B (HB3710)

    Description:

    Antibiotic

    Purity:

    >95%

    Pack:
    1mg
    Price:
    $178
    Qty:
  2. 2-APB (HB1208)

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    Description:

    IP3 receptor and store-operated channels (SOC) channel antagonist

    Purity:

    >98%

    Pack:
    10mg
    Price:
    $53
    Qty:
    Pack:
    50mg
    Price:
    $174
    Qty:
  3. Pack:
    50mg
    Price:
    $55
    Qty:
    Pack:
    250mg
    Price:
    $104
    Qty:
    Pack:
    1g
    Price:
    $349
    Qty:
  4. 7BIO (HB3732)

    Description:

    Aurora B and C kinase inhibitor

    Purity:

    >99%

    Pack:
    10mg
    Price:
    $174
    Qty:
    Pack:
    50mg
    Price:
    $704
    Qty:
  5. A11 (HB9579)

    Description:

    ANXA1 (Annexin A1) derived peptide. Blocks ANXA1-EphA2 interaction.

    Pack:
    1mg
    Price:
    $260
    Qty:
  6. Pack:
    1mg
    Price:
    $38
    Qty:
    Pack:
    5mg
    Price:
    $65
    Qty:
    Pack:
    10mg
    Price:
    $120
    Qty:
  7. Pack:
    10mg
    Price:
    $182
    Qty:
    Pack:
    50mg
    Price:
    $734
    Qty:
  8. A 83-01 (HB3218)

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    Description:

    Selective TGF-βRI (ALK5), ALK4 and ALK7 inhibitor. Maintains human hiPSC self renewal, 3D growth matrix component and promotes long-term organoid growth. Aids fibroblast to NSC/cardiomyocyte reprogramming.

    Purity:

    >98%

    Pack:
    5mg
    Price:
    $80
    Qty:
    Pack:
    25mg
    Price:
    $270
    Qty:
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