Histone deacetylase (HDAC)

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Histone acetylation is a key epigenetic process - it is upregulated during memory formation but downregulated in numerous neurodegenerative diseases (eg. Alzheimer's disease and Huntington's disease). There are 18 Histone Deacetylase (HDAC) enzymes that are classified into two groups, the histone deacetylase family and the sirtuin family. The histone deacetylase family is further divided into classes I, II and IV. HDAC inhibitors are a class of compounds that increase acetylation of lysine residues on histone proteins as well as other, nonhistone, proteins by inhibiting the activity of these HDAC enzymes. Researchers can save up to 50% on HDAC inhibitors from Hello Bio - they are up to half the price of other suppliers.

Items 1-10 of 1393

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  1. (D)-PPA 1 (HB7226)

    Description:

    PD-1/PD-L1 interaction inhibitor

    Pack:
    1mg
    Price:
    $200
    Qty:
  2. 1233B (HB3710)

    Description:

    Antibiotic

    Purity:

    >95%

    Pack:
    1mg
    Price:
    $196
    Qty:
  3. Description:

    Potent, highly selective iNOS inhibitor

    Purity:

    >98%

    Pack:
    25mg
    Price:
    $186
    Qty:
  4. 2-APB (HB1208)

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    Description:

    IP3 receptor and store-operated channels (SOC) channel antagonist

    Purity:

    >98%

    Pack:
    10mg
    Price:
    $58
    Qty:
    Pack:
    50mg
    Price:
    $191
    Qty:
  5. Description:

    20x wash buffer for use during immunolabeling techniques such as IHC.

    Pack:
    125mL
    Price:
    $127
    Qty:
    Pack:
    2x500mL
    Price:
    $235
    Qty:
  6. Description:

    20x Tris Buffered Saline wash buffer to remove non-specific binding and for use during immunolabeling techniques such as IHC.

    Pack:
    125mL
    Price:
    $92
    Qty:
    Pack:
    2x500mL
    Price:
    $162
    Qty:
  7. Pack:
    50mg
    Price:
    $62
    Qty:
    Pack:
    250mg
    Price:
    $116
    Qty:
    Pack:
    1g
    Price:
    $391
    Qty:
  8. 7BIO (HB3732)

    Description:

    Aurora B and C kinase inhibitor

    Purity:

    >99%

    Pack:
    10mg
    Price:
    $191
    Qty:
    Pack:
    50mg
    Price:
    $774
    Qty:
  9. A11 (HB9579)

    Description:

    ANXA1 (Annexin A1) derived peptide. Blocks ANXA1-EphA2 interaction.

    Pack:
    1mg
    Price:
    $286
    Qty:
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