Histone deacetylase (HDAC)

Histone acetylation is a key epigenetic process - it is upregulated during memory formation but downregulated in numerous neurodegenerative diseases (eg. Alzheimer's disease and Huntington's disease). There are 18 Histone Deacetylase (HDAC) enzymes that are classified into two groups, the histone deacetylase family and the sirtuin family. The histone deacetylase family is further divided into classes I, II and IV. HDAC inhibitors are a class of compounds that increase acetylation of lysine residues on histone proteins as well as other, nonhistone, proteins by inhibiting the activity of these HDAC enzymes. Researchers can save up to 50% on HDAC inhibitors from Hello Bio - they are up to half the price of other suppliers.

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  1. MM 47755 (HB3977)

    Description:

    Antibiotic with antifungal and antibacterial actions

    Purity:

    >98%

    Pack:
    5mg
    Price:
    $526
    Qty:
  2. Description:

    Novel caged, fast-equilibrating glutamate receptor antagonist. Suitable for use as a synaptic probe.

    Purity:

    >98%

    Pack:
    10mg
    Price:
    $198
    Qty:
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    Description:

    Caged glutamate that rapidly and efficiently releases glutamate when photolysed

    Purity:

    >98%

    Pack:
    10mg
    Price:
    $173
    Qty:
    Pack:
    50mg
    Price:
    $715
    Qty:
    Pack:
    10mM (add 1ml water)
    Price:
    $95
    Qty:
    Pack:
    50mM (add 1ml water)
    Price:
    $401
    Qty:
  4. Moclobemide (HB1791)

    Description:

    Reversible MAO-A inhibitor

    Purity:

    >99%

    Pack:
    10mg
    Price:
    $109
    Qty:
    Pack:
    50mg
    Price:
    $436
    Qty:
  5. Pack:
    125mL
    Price:
    $75
    Qty:
    Pack:
    250mL
    Price:
    $146
    Qty:
    Pack:
    2 x 250ml
    Price:
    $146
    Qty:
  6. MOG (35-55) (HB5273)

    Description:

    Myelin oligodendrocyte glycoprotein fragment. Induces experimental multiple sclerosis-like disease.

    Purity:

    >95%

    Pack:
    1mg
    Price:
    $176
    Qty:
  7. MOMBA (HB7626)

    Description:

    Newly identified, highly selective FFA2-DREADD agonist

    Purity:

    >98%

    Pack:
    250mg
    Price:
    $50
    Qty:
  8. Pack:
    500mg
    Price:
    $40
    Qty:
    Pack:
    1g
    Price:
    $76
    Qty:
  9. Pack:
    5mg
    Price:
    $217
    Qty:
    Pack:
    25mg
    Price:
    $845
    Qty:
  10. Description:

    NLRP3/NALP3 inflammasome activator

    Pack:
    10mg
    Price:
    $552
    Qty:
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