D-NG-Monomethylarginine (D-NMMA)
(HB0260)
Product overview
Name | D-NG-Monomethylarginine (D-NMMA) |
Description | Inactive enantiomer of L-NMMA |
Purity | >98% |
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Biological Data
Biological description | Inactive enantiomer of NG-Monomethyl-L-arginine (L-NMMA), a competitive NOS inhibitor. At a concentration of 100 µM D-NMMA does not inhibit NOS. Used as a negative control for L-NMMA. Cell permeable. |
Solubility & Handling
Storage instructions | +4°C |
Solubility overview | Soluble in water (1mg/ml) or methanol |
Important | This product is for RESEARCH USE ONLY and is not intended for therapeutic or diagnostic use. Not for human or veterinary use. |
Chemical Data
Molecular Weight | 248.3 |
Chemical structure | |
Molecular Formula | C7H16N4O2 CH3COOH |
CAS Number | 137694-75-8 |
PubChem identifier | 5702206 |
SMILES | CC(=O)O.CN=C(N)NCCCC(C(=O)O)N |
References for D-NG-Monomethylarginine (D-NMMA)
References are publications that support the biological activity of the product
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Endogenous nitric oxide as a modulator of rabbit skeletal muscle microcirculation in vivo.
Persson MG et al (1990) Br J Pharmacol 100(3) : 463-6. -
A specific inhibitor of nitric oxide formation from L-arginine attenuates endothelium-dependent relaxation.
Rees DD et al (1989) Br J Pharmacol 96(2) : 418-24.