D-NG-Monomethylarginine (D-NMMA)

(HB0260)

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Product overview

Name D-NG-Monomethylarginine (D-NMMA)
Purity >98%
Description Inactive enantiomer of L-NMMA
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Biological Data

Biological description Inactive enantiomer of NG-Monomethyl-L-arginine (L-NMMA), a competitive NOS inhibitor. At a concentration of 100 µM D-NMMA does not inhibit NOS. Used as a negative control for L-NMMA. Cell permeable.

Solubility & Handling

Solubility overview Soluble in water (1mg/ml) or methanol
Storage instructions +4°C
Storage of solutions Prepare and use solutions on the same day if possible. Store solutions at -20°C for up to one month if storage is required. Equilibrate to RT and ensure the solution is precipitate free before use.
Shipping Conditions Stable for ambient temperature shipping. Follow storage instructions on receipt.
Important This product is for RESEARCH USE ONLY and is not intended for therapeutic or diagnostic use. Not for human or veterinary use.

Calculators

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Dilution

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Chemical Data

Purity >98%
Molecular Weight 248.3
Chemical structure D-NG-Monomethylarginine (D-NMMA) [137694-75-8] Chemical Structure
Molecular Formula C7H16N4O2 CH3COOH
CAS Number 137694-75-8
PubChem identifier 5702206
SMILES CC(=O)O.CN=C(N)NCCCC(C(=O)O)N

References for D-NG-Monomethylarginine (D-NMMA)

References are publications that support the biological activity of the product
  • Endogenous nitric oxide as a modulator of rabbit skeletal muscle microcirculation in vivo.

    Persson MG et al (1990) Br J Pharmacol 100(3) : 463-6.
  • A specific inhibitor of nitric oxide formation from L-arginine attenuates endothelium-dependent relaxation.

    Rees DD et al (1989) Br J Pharmacol 96(2) : 418-24.

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