D-NG-Monomethylarginine (D-NMMA)
(HB0260)
Product overview
| Name | D-NG-Monomethylarginine (D-NMMA) |
| Description | Inactive enantiomer of L-NMMA |
| Purity | >98% |
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Biological Data
| Biological description | Inactive enantiomer of NG-Monomethyl-L-arginine (L-NMMA), a competitive NOS inhibitor. At a concentration of 100 µM D-NMMA does not inhibit NOS. Used as a negative control for L-NMMA. Cell permeable. |
Solubility & Handling
| Storage instructions | +4°C |
| Solubility overview | Soluble in water (1mg/ml) or methanol |
| Important | This product is for RESEARCH USE ONLY and is not intended for therapeutic or diagnostic use. Not for human or veterinary use. |
Chemical Data
| Molecular Weight | 248.3 |
| Chemical structure | ![D-NG-Monomethylarginine (D-NMMA) [137694-75-8] Chemical Structure](https://hellobio.com/media/catalog/product//h/b/hb0260.png "D-NG-Monomethylarginine (D-NMMA) [137694-75-8]") |
| Molecular Formula | C7H16N4O2 CH3COOH |
| CAS Number | 137694-75-8 |
| PubChem identifier | 5702206 |
| SMILES | CC(=O)O.CN=C(N)NCCCC(C(=O)O)N |
References for D-NG-Monomethylarginine (D-NMMA)
References are publications that support the biological activity of the product
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Endogenous nitric oxide as a modulator of rabbit skeletal muscle microcirculation in vivo.
Persson MG et al (1990) Br J Pharmacol 100(3) : 463-6. -
A specific inhibitor of nitric oxide formation from L-arginine attenuates endothelium-dependent relaxation.
Rees DD et al (1989) Br J Pharmacol 96(2) : 418-24.
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