Histone deacetylase (HDAC)

Histone acetylation is a key epigenetic process - it is upregulated during memory formation but downregulated in numerous neurodegenerative diseases (eg. Alzheimer's disease and Huntington's disease). There are 18 Histone Deacetylase (HDAC) enzymes that are classified into two groups, the histone deacetylase family and the sirtuin family. The histone deacetylase family is further divided into classes I, II and IV. HDAC inhibitors are a class of compounds that increase acetylation of lysine residues on histone proteins as well as other, nonhistone, proteins by inhibiting the activity of these HDAC enzymes. Researchers can save up to 50% on HDAC inhibitors from Hello Bio - they are up to half the price of other suppliers.

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  1. Pyripyropene A (HB4044)

    Description:

    Highly specific acyl-coenzyme A cholesterol acetyltransferase 2 inhibitor

    Purity:

    >95%

    Pack:
    250μg
    Price:
    $184
    Qty:
    Pack:
    1mg
    Price:
    $554
    Qty:
  2. Quinolactacin A (HB4047)

    Description:

    Acetylcholinesterase (AChE) inhibitor

    Purity:

    >95%

    Pack:
    5mg
    Price:
    $496
    Qty:
  3. Q-VD-OPh (HB4048)

    Description:

    Cell permeable, irreversible and non-toxic pan-caspase inhibitor

    Purity:

    >95%

    Pack:
    1mg
    Price:
    $241
    Qty:
    Pack:
    5mg
    Price:
    $985
    Qty:
  4. Description:

    Cell permeable, non-toxic negative control for Q-VD-Oph

    Purity:

    >95%

    Pack:
    1mg
    Price:
    $229
    Qty:
  5. Rapamycin (HB2779)

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    Description:

    mTOR inhibitor and potent immunosuppressant. Also used in inducible gene editing methods (e.g. CRISPR/Cas9) and promotes hPSC differentiation.

    Purity:

    >98%

    Pack:
    1mg
    Price:
    $146
    Free trial
    Qty:
    Pack:
    5mg
    Price:
    $247
    Qty:
  6. Rebeccamycin (HB4052)

    Description:

    Weak topoisomerase I inhibitor. Shows no activity against protein kninases.

    Purity:

    >98%

    Pack:
    1mg
    Price:
    $479
    Qty:
  7. Resveratrol (HB4055)

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    Description:

    Potent phenolic antioxidant with many biological actions. COX-1 inhibitor.

    Purity:

    >98%

    Pack:
    50mg
    Price:
    $52
    Qty:
    Pack:
    100mg
    Price:
    $88
    Qty:
    Pack:
    500mg
    Price:
    $206
    Qty:
  8. Reticulol (HB4057)

    Description:

    Topoisomerase I (Topo I) inhibitor.

    Purity:

    >98%

    Pack:
    1mg
    Price:
    $195
    Qty:
  9. RG 108 (HB1377)

    Description:

    Non-nucleoside DNA methyltransferase inhibitor. Enhances iPSC generation efficiency.

    Purity:

    >99%

    Pack:
    10mg
    Price:
    $98
    Qty:
    Pack:
    50mg
    Price:
    $386
    Qty:
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