Histone deacetylase (HDAC)

Histone acetylation is a key epigenetic process - it is upregulated during memory formation but downregulated in numerous neurodegenerative diseases (eg. Alzheimer's disease and Huntington's disease). There are 18 Histone Deacetylase (HDAC) enzymes that are classified into two groups, the histone deacetylase family and the sirtuin family. The histone deacetylase family is further divided into classes I, II and IV. HDAC inhibitors are a class of compounds that increase acetylation of lysine residues on histone proteins as well as other, nonhistone, proteins by inhibiting the activity of these HDAC enzymes. Researchers can save up to 50% on HDAC inhibitors from Hello Bio - they are up to half the price of other suppliers.

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  1. Rubratoxin A (HB4063)

    Description:

    Potent, selective, competitive PP2A inhibitor

    Purity:

    >95%

    Pack:
    250μg
    Price:
    $357
    Qty:
    Pack:
    500μg
    Price:
    $595
    Qty:
  2. Rubrofusarin (HB4064)

    Description:

    Moderate tyrosinase inhibitor

    Purity:

    >98%

    Pack:
    5mg
    Price:
    $398
    Qty:
  3. γ-Rubromycin (HB3907)

    Description:

    Telomerase inhibitor

    Purity:

    >98%

    Pack:
    5mg
    Price:
    $401
    Qty:
  4. RWJ 67657 (HB1300)

    Description:

    Potent p38 MAPK inhibitor

    Purity:

    >98%

    Pack:
    1mg
    Price:
    $52
    Qty:
    Pack:
    5mg
    Price:
    $88
    Qty:
    Pack:
    10mg
    Price:
    $162
    Qty:
  5. S14161 (HB4068)

    Description:

    pan Class I PI3K isoforms inhibitor

    Purity:

    >99%

    Pack:
    5mg
    Price:
    $367
    Qty:
  6. Pack:
    10mg
    Price:
    $120
    Qty:
    Pack:
    50mg
    Price:
    $338
    Qty:
  7. Pack:
    5mg
    Price:
    $121
    Qty:
    Pack:
    10mg
    Price:
    $182
    Qty:
    Pack:
    25mg
    Price:
    $389
    Qty:
  8. Sarcophine (HB4076)

    Description:

    Acetylcholine esterase and ATPase inhibitor

    Purity:

    >97%

    Pack:
    10mg
    Price:
    $496
    Qty:
  9. SB 202190 (HB1301)

    Description:

    Potent ATP competitive p38 MAPK inhibitor. 3D growth matrix component, promotes long-term organoid growth and can be used in production of gastric organoids. Promotes stability of human pluripotent stem cells.

    Purity:

    >99%

    Pack:
    5mg
    Price:
    Qty:
    Pack:
    10mg
    Price:
    $137
    Qty:
    Pack:
    25mg
    Price:
    $339
    Qty:
    Pack:
    50mg
    Price:
    $570
    Qty:
  10. SB 203580 (HB1302)

    Description:

    Potent, selective p38 MAPK inhibitor. Stimulates neural stem cell proliferation.

    Purity:

    >98%

    Pack:
    500μg
    Price:
    $47
    Qty:
    Pack:
    1mg
    Price:
    Qty:
    Pack:
    10mg
    Price:
    $191
    Qty:
    Pack:
    50mg
    Price:
    $703
    Qty:
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