Histone deacetylase (HDAC)

Histone acetylation is a key epigenetic process - it is upregulated during memory formation but downregulated in numerous neurodegenerative diseases (eg. Alzheimer's disease and Huntington's disease). There are 18 Histone Deacetylase (HDAC) enzymes that are classified into two groups, the histone deacetylase family and the sirtuin family. The histone deacetylase family is further divided into classes I, II and IV. HDAC inhibitors are a class of compounds that increase acetylation of lysine residues on histone proteins as well as other, nonhistone, proteins by inhibiting the activity of these HDAC enzymes. Researchers can save up to 50% on HDAC inhibitors from Hello Bio - they are up to half the price of other suppliers.

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  4. Description:

    Endogenous HDAC1, HDAC3 and HDAC4 inhibitor

    Purity:

    >98%

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    25mg
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    $56
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  5. Description:

    Endogenous HDAC1, HDAC3 and HDAC4 inhibitor

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    >98%

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    25mg
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    $49
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    $112
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  6. Description:

    Specific and irreversible HMG-CoA synthase inhibitor

    Purity:

    >95%

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    500μg
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    $216
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    1mg
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    $383
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  7. Description:

    Pan kinase inhibitor. Potently inhibits MEK1, Cdk1, Cdk2, Cdk3 and Cdk5 and GSK-3β.

    Purity:

    >97%

    Pack:
    250μg
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    $207
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    1mg
    Price:
    $689
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  8. IBMX (HB3000)

    Description:

    Non-selective, competitive cAMP and cGMP PDE inhibitor. Facilitates neural progenitor cell differentiation.

    Purity:

    >98%

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    100mg
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    500mg
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    $138
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  9. Ibrutinib (HB4204)

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    Description:

    Potent, selective Bruton's tyrosine kinase (BTK) inhibitor.

    Purity:

    >98%

    Pack:
    5mg
    Price:
    $156
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    25mg
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    $469
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