Hedgehog signaling

Hedgehog signaling inhibitor. Also cholesterol synthesis inhibitor.

Selective antagonist for GluN2D subunit containing NMDA receptors

Highly potent, selective GluN2C/2D NMDAR antagonist

Potent, selective GluK1 subunit selective kainate receptor antagonist

Potent, selective GluK1 / GluK3 subunit selective kainate receptor antagonist

Novel NMDAR pan-PAM

NMDAR pan-PAM that potentiates all GluN2 subunits. Enhances LTD and decreases LTP. 

NMDAR PAM which potentiates GluN2A and GluN2B with minimal effects on 2C and 2D.

UCPH-101 is a potent, selective, non-competitive EAAT1 inhibitor

Selective EAAT1 inhibitor