My Cart
My account
Menu
Main Menu

Thapsigargin

(HB1118)
Be the first to add a publication
Technical documents: SDS CoA Datasheet
2  Reviews
Top Reviews:
100% of 100
Add Your Review
Add to Wish List

Product overview

Name Thapsigargin
Purity >97%
Description Potent, non-competitive SERCA inhibitor
Biological Data Solubility & Handling Chemical Data Related Areas Calculators Technical guides (1) Reviews (2) References (3) Frequently bought together
Write Your Own Review
You're reviewing:Thapsigargin
Rate this item:

Images

Thapsigargin product vial image | Hello Bio
Thapsigargin product vial image | Hello Bio

Thapsigargin product vial image | Hello Bio

Thapsigargin product vial image | Hello Bio

Biological Data

Biological description Potent and non-competitive sarco-endoplasmic Ca2+-ATPase (SERCA) inhibitor. Activates endoplasmic reticulum stress mechanisms. Induces apoptosis in most cells. Shows anticancer and neuroprotective actions.

Solubility & Handling

Solubility overview Soluble in DMSO (100mM)
Storage instructions -20°C (desiccate)
Storage of solutions Prepare and use solutions on the same day if possible. Store solutions at -20°C for up to one month if storage is required. Equilibrate to RT and ensure the solution is precipitate free before use.
Shipping Conditions Stable for ambient temperature shipping. Follow storage instructions on receipt.
Important This product is for RESEARCH USE ONLY and is not intended for therapeutic or diagnostic use. Not for human or veterinary use.

Calculators

Molarity

=
x
x
More Info

Dilution

x
=
x
More Info

Chemical Data

Purity >97%
Chemical name (3S,3aR,4S,6S,6AR,7S,8S,9bS)-6-(Acetyloxy)-2,3,3a,4,5,6,6a,7,8,9b- decahydro-3,3a-dihydroxy-3,6,9-trimethyl-8-[[(2Z)-2-methyl-1-oxo-2-butenyl]oxy]-2-oxo-4-(1-oxobutoxy)azuleno[4,5-b]furan-7-yl octanoate
Molecular Weight 650.76
Chemical structure Thapsigargin [67526-95-8] Chemical Structure
Molecular Formula C34H50O12
CAS Number 67526-95-8
PubChem identifier 446378
SMILES CCCCCCCC(=O)O[C@H]1[C@H]2C(=C([C@@H]1OC(=O)/C(=C\C)/C)C)[C@H]3[C@]([C@H](C[C@]2(C)OC(=O)C)OC(=O)CCC)([C@](C(=O)O3)(C)O)O
InChi InChI=1S/C34H50O12/c1-9-12-13-14-15-17-24(37)43-28-26-25(20(5)27(28)44-30(38)19(4)11-3)29-34(41,33(8,40)31(39)45-29)22(42-23(36)16-10-2)18-32(26,7)46-21(6)35/h11,22,26-29,40-41H,9-10,12-18H2,1-8H3/b19-11-/t22-,26+,27-,28-,29-,32-,33+,34+/m0/s1
InChiKey IXFPJGBNCFXKPI-FSIHEZPISA-N
MDL number MFCD00083511

References for Thapsigargin

References are publications that support the biological activity of the product

3 Item(s)

Related Products
Grouped product items
Order: HB1118
Pack PriceQty
1mg
$84
5mg
$378
10mg
$671
Potent, non-competitive SERCA inhibitor
Shipping Info

Standard: $35

Hazardous: $35

Shipped on ice: $35

Shipping will be calculated at checkout

Contact Us

Call 609-683-7500
Fax 609-228-4994

customercare-usa@hellobio.com

Related Products

Ryanodine
Code:
HB1320
Pack:
1mg, 5mg
Price:
$171, $769
Potent Ca2+ release inhibitor
Iberiotoxin
Code:
HB1053
Pack:
100μg
Price:
$253
Potent, reversible, selective KCa channel inhibitor
Cyclopiazonic acid
Code:
HB1117
Pack:
10mg, 50mg
Price:
$99, $470
Potent SERCA1a inhibitor