Product overview

Name Tertiapin LQ
Purity >95%
Description Potent, selective Kir1.1 channel blocker
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Images

Tertiapin LQ product vial image | Hello Bio

Biological Data

Biological description Tertiapin-Q derivative. Potent and selective Kir1.1 channel blocker. Selective for Kir1.1 over Kir3.1/3.2 and Kir3.1/3.4 (Kd values are 1.1, 274 and 361 nM respectively).

Solubility & Handling

Solubility overview Soluble in acetonitrile (2mg/ml)
Storage instructions -20°C
Storage of solutions Prepare and use solutions on the same day if possible. Store solutions at -20°C for up to one month if storage is required. Equilibrate to RT and ensure the solution is precipitate free before use.
Shipping Conditions Stable for ambient temperature shipping. Follow storage instructions on receipt.
Important This product is for RESEARCH USE ONLY and is not intended for therapeutic or diagnostic use. Not for human or veterinary use.

Calculators

Molarity

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Dilution

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Chemical Data

Purity >95%
Molecular Weight 2428.03
Molecular Formula C106H179N33O24S4
PubChem identifier 90488935
SMILES [H]N[C@@H](C)C(=O)N[C@@H](CC(C)C)C(=O)N[C@H]1CSSC[C@@H]2NC(=O)[C@H](CCC(N)=O)NC(=O)[C@H](CC(C)C)NC(=O)[C@@H]3CCCN3C(=O)[C@@H](NC(=O)[C@@H](NC(=O)[C@@H](NC(=O)[C@H](CCCNC(N)=N)NC(=O)[C@H](CC(N)=O)NC(=O)[C@H](CSSC[C@H](NC(=O)[C@H](CCCCN)NC(=O)[C@H](CCCCN)NC(=O)[C@H](CC3=CNC4=C3C=CC=C4)NC2=O)C(=O)NCC(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCCCN)C(N)=O)NC(=O)[C@H](CC(N)=O)NC1=O)[C@@H](C)CC)[C@@H](C)CC)[C@@H](C)CC
InChiKey WUMIWMIQOSXVPZ-ZPWFPUPGSA-N

References for Tertiapin LQ

References are publications that support the biological activity of the product
  • Engineered specific and high-affinity inhibitor for a subtype of inward-rectifier K+ channels.

    Ramu Y et al (2008) Proc Natl Acad Sci U S A 105(31) : 10774-8.

1 Item