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Biological Data
| Biological description | Non-selective K+ channel blocker. Induces synaptic plasticity in the hippocampus. Causes vascular smooth muscle contractions. |
Solubility & Handling
| Storage instructions | Room temperature (desiccate) |
| Solubility overview | Soluble in water (100mM) |
| Important | This product is for RESEARCH USE ONLY and is not intended for therapeutic or diagnostic use. Not for human or veterinary use. |
Chemical Data
| Chemical name | N,N,N,N-Tetraethylammonium chloride |
| Chemical structure | ![Tetraethylammonium chloride [56-34-8] Chemical Structure](data:image/png;base64,iVBORw0KGgoAAAANSUhEUgAAAAEAAAABCAQAAAC1HAwCAAAAC0lEQVR4nGP6zwAAAgcBApocMXEAAAAASUVORK5CYII= "Tetraethylammonium chloride [56-34-8]") |
| Molecular Formula | C8H20ClN |
| SMILES | CC[N+](CC)(CC)CC.[Cl-] |
| InChi | InChI=1S/C8H20N.ClH/c1-5-9(6-2,7-3)8-4;/h5-8H2,1-4H3;1H/q+1;/p-1 |
| InChiKey | YMBCJWGVCUEGHA-UHFFFAOYSA-M |
Publications
These publications cite the use of Tetraethylammonium chloride (TEA) purchased from Hello Bio:
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Two opposing hippocampus to prefrontal cortex pathways for the control of approach and avoidance behaviour
Sanchez-Bellot C et al (2022) Nat Commun 13(1) : 339 -
Hippocampal ghrelin signalling informs the decision to eat
MacAskill et al (2021) bioRxiv https://doi.org/10.1101/2021.11.05.467326 : doi -
An Etiological Foxp2 Mutation Impairs Neuronal Gain in Layer VI Cortico-Thalamic Cells through Increased GABAB/GIRK Signaling
Druart M et al (2020) J Neurosci 40(44) : 8543-8555 -
Investigating dichotomous projections from ventral hippocampus to prefrontal cortex
Sanchez Bellot et al (2020) UCL : Thesis -
Push-pull regulation of exploratory behavior by two opposing hippocampal to prefrontal cortex pathways
Sánchez-Bellot et al (2019) bioRxiv https://doi.org/10.1101/2019.12.18.880831 : doi
Non-selective K+ channel blocker
![Tetraethylammonium chloride [56-34-8] Chemical Structure](https://hellobio.com/media/catalog/product//h/b/hb1088.png "Tetraethylammonium chloride [56-34-8]")
Understanding purity and quality - a guide for life scientists
