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Inflammasome
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Inflammasomes are an important part of the innate immune system which are activated upon cellular infection or stress to trigger maturation of proinflammatory cytokines. They regulate the activation of caspase-1 and induce an inflammatory response.
2-APB (HB1208)
Description:IP3 receptor and store-operated channels (SOC) channel antagonist
Purity:>98%
- Description:
Neurotoxin, widely used to produce the 6-OHDA Parkinson’s disease model
Purity:>98%
A 769662 (HB1351)
Description:Potent, reversible AMPK activator. Inhibits MSC proliferation.
Purity:>98%
A 83-01 (HB3218)
Description:Selective TGF-βRI (ALK5), ALK4 and ALK7 inhibitor. Maintains human hiPSC self renewal, 3D growth matrix component and promotes long-term organoid growth. Aids fibroblast to NSC/cardiomyocyte reprogramming.
Purity:>98%