Cytoskeleton and Extracellular Matrix
The cytoskeleton acts as a cellular scafforld within a cell and plays an important role in many processes such as cell motility and cell division. Many cytoskeletal proteins interact with proteins of the extracellular matrix (ECM). The ECM is a network of extracellular molecules which provide structural and biochemical support to surrounding. The ECM is vital to cellular processes including proliferation, adhesion, migration, polarity, differentiation, and apoptosis.
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View products: Actin | Matrix Metalloproteases (MMP) | PI3K/Akt/mTOR | Microtubule | ROCK (Rho-kinase)
Pluripotin (HB2223)
Description:Dual ERK1/RasGAP inhibitor. Maintains ESC self-renewal.
Purity:>98%
PluriSln 1 (HB3573)
Description:SCD1 inhibitor. Selectively eliminates undifferentiated hPSCs from culture.
Purity:>99%
Pexidartinib (PLX3397) (HB8991)
Description:Potent CSF-1R inhibitor. Widely used microglia-depletion agent.
Purity:>98%
PLX4720 (HB4030)
Description:Potent and selective cell permeable B-Raf and C-Raf inhibitor
Purity:>99%
PLX5622 (HB17582)
Description:Highly selective, potent CSF-1R inhibitor. Widely used microglia-depletion agent.
Purity:>98%
PNU 37883 hydrochloride (HB1105)
Description:Selective vascular KATP channel antagonist
Purity:>99%
PNU 74654 (HB0528)
Description:β-catenin inhibitor. Wnt pathway inhibitor. Promotes neural differentiation of hPSCs.
Purity:>99%