Antagonists & inhibitors

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An antagonist is a drug or chemical that reduces the effect of an agonist. Competitive antagonists bind to the same site on a receptor as the agonist but do not activate it - thereby blocking the action of the agonist. Non-competitive antagonists block the action of the agonist by binding to a different site on the receptor (an allosteric or non-agonist site). A reversible antagonist binds non-covalently and can be washed out. An irreversible antagonist binds covalently and cannot be displaced by either competing ligands or washing. Inhibitors are drugs that can bind to a protein, such as an enzyme and decrease its activity. Researchers can save up to 50% on competitive antagonists, non-competitive antagonists, reversible and irreversible antagonists, and inhibitors from Hello Bio - they are up to half the price of other suppliers.

Items 161-170 of 359

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  1. 17  Reviews
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    Description:

    Estrogen receptor ligand. For inducible genome manipulation (e.g. Cre-LoxP (CreER)/ TRAP/ CRISPR-Cas9).

    Purity:

    >98%

    Pack:
    10mg
    Price:
    $69
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    50mg
    Price:
    $239
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    1mg
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    Pack:
    10mg
    Price:
    $107
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    50mg
    Price:
    $248
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  3. Imiquimod (HB3109)

    1  Review
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    Description:

    Toll-like receptor 7 (TLR7) agonist

    Purity:

    >98%

    Pack:
    100mg
    Price:
    $88
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    Pack:
    250mg
    Price:
    $174
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  4. Description:

    Water soluble Toll-like receptor 7 (TLR7) agonist. Stimulates cytokine production.

    Purity:

    >98%

    Pack:
    5mg
    Price:
    $28
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    Pack:
    50mg
    Price:
    $50
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    Pack:
    100mg
    Price:
    $75
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    Pack:
    250mg
    Price:
    $143
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  5. Iperoxo (HB9785)

    Description:

    Potent muscarinic acetylcholine receptor superagonist. Also binds the hM3R-miniGq DREADD receptor.

    Pack:
    1mg
    Price:
    $46
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    10mg
    Price:
    $155
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    50mg
    Price:
    $614
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  6. Ipsapirone (HB1699)

    Description:

    Selective 5-HT1A agonist

    Purity:

    >99%

    Pack:
    10mg
    Price:
    $119
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    Pack:
    50mg
    Price:
    $451
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  7. Pack:
    10mg
    Price:
    $135
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    Pack:
    50mg
    Price:
    $571
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  8. ITD 1 (HB3446)

    Description:

    Selective TGF-β signaling inhibitor. Induces cardiomyocyte differentiation in ESCs.

    Purity:

    >98%

    Pack:
    10mg
    Price:
    $213
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    Pack:
    50mg
    Price:
    $824
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  9. Description:

    Novel, inactive photocaged derivative of raseglurant which can be uncaged with violet light. Shows light-dependent analgesic activity in vivo.

    Purity:

    >98%

    Pack:
    1mg
    Price:
    $66
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    Pack:
    5mg
    Price:
    $312
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