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Solubility & Handling Storage instructions -20°C (desiccate)
Solubility overview Soluble in water (0.5 mg/ml)
Important This product is for RESEARCH USE ONLY and is not intended for therapeutic or diagnostic use. Not for human or veterinary use
Chemical Data Chemical name DEEAVYFAHLDIIW
(Asp-1 = Suc-Asp)
Chemical structure
Molecular Formula C86 H117 N17 O27
Sequence (one letter) DEEAVYFAHLDIIW
Sequence (three letter) Asp-Glu-Glu-Ala-Val-Tyr-Phe-Ala-His-Leu-Asp-Ile-Ile-Trp
Modifications Asp-1 = Suc-Asp
PubChem identifier 16133819
SMILES CC[C@H](C)[C@@H](C(=O)N[C@@H]([C@@H](C)CC)C(=O)N[C@@H](CC1=CNC2=CC=CC=C21)C(=O)O)NC(=O)[C@H](CC(=O)O)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](CC3=CNC=N3)NC(=O)[C@H](C)NC(=O)[C@H](CC4=CC=CC=C4)NC(=O)[C@H](CC5=CC=C(C=C5)O)NC(=O)[C@H](C(C)C)NC(=O)[C@H](C)NC(=O)[C@H](CCC(=O)O)NC(=O)[C@H](CCC(=O)O)NC(=O)[C@H](CC(=O)O)NC(=O)CCC(=O)O
InChiKey DXPHNGAMYPPTBJ-TZMIJSMNSA-N
References for IRL-1620 References are publications that support the biological activity of the product
Neuroprotective Effect of IRL-1620, an Endothelin B Receptor Agonist, on a Pediatric Rat Model of Middle Cerebral Artery Occlusion Cifuentes EG et al (2018) Front Pediatr 6 : 310 Stimulation of endothelin B receptors by IRL-1620 decreases the progression of Alzheimer's disease Briyal S et al (2015) Neuroscience 301 : 01-11 Endothelin B receptor agonist, IRL 1620, enhances the anti-tumor efficacy of paclitaxel in breast tumor rats Rajeshkumar NV et al (2005) Breast Cancer Res Treat 94(3) : 237-47 A potent and specific agonist, Suc-[Glu9,Ala11,15]-endothelin-1(8-21), IRL 1620, for the ETB receptor Takai M et al (1992) Biochem Biophys Res Commun 184(2) : 953-9
Highly selective ETB agonist
![IRL-1620 [142569-99-1] Chemical Structure](https://hellobio.com/media/catalog/product//h/b/hb3411_1.png "IRL-1620 [142569-99-1]")
Understanding purity and quality - a guide for life scientists
