Antagonists & inhibitors

An antagonist is a drug or chemical that reduces the effect of an agonist. Competitive antagonists bind to the same site on a receptor as the agonist but do not activate it - thereby blocking the action of the agonist. Non-competitive antagonists block the action of the agonist by binding to a different site on the receptor (an allosteric or non-agonist site). A reversible antagonist binds non-covalently and can be washed out. An irreversible antagonist binds covalently and cannot be displaced by either competing ligands or washing. Inhibitors are drugs that can bind to a protein, such as an enzyme and decrease its activity. Researchers can save up to 50% on competitive antagonists, non-competitive antagonists, reversible and irreversible antagonists, and inhibitors from Hello Bio - they are up to half the price of other suppliers.

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10 Items

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  1. Altenusin (HB3755)

    Description:

    Non-competitive, specific neutral sphingomyelinase (N-SMase) inhibitor.

    Purity:

    >97%

    Pack:
    1mg
    Price:
    $183
    Qty:
    Pack:
    5mg
    Price:
    $635
    Qty:
  2. Description:

    Potent adenosine deaminase and PDE2 inhibitor. Supresses spontaneous hESC differentiation. Also maintains pluripotency of hESCs in the absence of exogenous cytokines.

    Purity:

    >98%

    Pack:
    10mg
    Price:
    $109
    Qty:
    Pack:
    25mg
    Price:
    $250
    Qty:
  3. IBMX (HB3000)

    Description:

    Non-selective, competitive cAMP and cGMP PDE inhibitor. Facilitates neural progenitor cell differentiation.

    Purity:

    >98%

    Pack:
    100mg
    Price:
    Qty:
    Pack:
    500mg
    Price:
    $134
    Qty:
  4. Pack:
    50mg
    Price:
    $108
    Qty:
    Pack:
    100mg
    Price:
    $173
    Qty:
    Pack:
    250mg
    Price:
    $350
    Qty:
    Pack:
    500mg
    Price:
    $647
    Qty:
  5. Obscurolide A1 (HB4003)

    Description:

    Phosphodiesterase inhibitor.

    Purity:

    >98%

    Pack:
    5mg
    Price:
    $496
    Qty:
  6. Description:

    Potent, selective PDE4 inhibitor. Enantiomer of Rolipram.

    Purity:

    >98%

    Pack:
    10mg
    Price:
    $208
    Qty:
    Pack:
    50mg
    Price:
    $807
    Qty:
  7. (R,S)-Rolipram (HB2896)

    Description:

    Selective PDE4 inhibitor

    Purity:

    >98%

    Pack:
    10mg
    Price:
    $135
    Qty:
  8. Description:

    PDE4 inhibitor. Less potent enantiomer of Rolipram.

    Pack:
    50mg
    Price:
    $565
    Qty:
  9. Sericic acid (HB4081)

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    Description:

    Phosphodiesterase 4 (PDE4) inhibitor with various biological actions

    Purity:

    >95%

    Pack:
    25mg
    Price:
    $509
    Qty: