Agonists & activators
An agonist or activator, is a drug or chemical that binds to and activates a protein, such as receptor or enzyme. Full agonists have high efficacy, eliciting a full response whilst occupying a small proportion of receptors. Partial agonists have a lower efficacy and cannot produce a maximal response, even if occupying a high proportion of receptors. Inverse agonists can bind to the same receptor binding-site as an agonist, but elicit an opposite effect. Researchers can save up to 50% on activators, agonists, partial agonists and inverse agonists from Hello Bio - they are up to half the price of other suppliers.
Cyclosporin A (HB0220)
Description:Potent calcineurin inhibitor. Inhibits MPTP opening.
Purity:>99%
Cyclosporin D (HB3860)
Description:Calcineurin inhibitor. Potent inhibitor of tumor promoting phorbol ester (TPA/PMA) effects.
Purity:>97%
Cyclothiazide (HB0221)
Description:AMPA receptor positive allosteric modulator. Inhibits AMPAR desensitization.
Purity:>98%