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Biological Data
Biological description | Potent inhibitor of tumor promoting phorbol ester TPA/PMA effects in vivo. Antifungal. Moderate immunosuppressant. Calcineurin inhibitor with lower activity than Cyclosporin A.Moderate inhibitor of formyl peptide-induced superoxide formation. |
Solubility & Handling
Storage instructions | +4°C |
Important | This product is for RESEARCH USE ONLY and is not intended for therapeutic or diagnostic use. Not for human or veterinary use. |
Chemical Data
Chemical structure | |
SMILES | C/C=C/C[C@@H](C)[C@@H](O)C1N(C)C(=O)[C@H](C(C)C)N(C)C(=O)[C@H](CC(C)C)N(C)C(=O)[C@H](CC(C)C)N(C)C(=O)[C@@H](C)NC(=O)[C@H](C)NC(=O)[C@H](CC(C)C)N(C)C(=O)[C@@H](NC(=O)[C@H](CC(C)C)N(C)C(=O)CN(C)C(=O)[C@@H](NC1=O)C(C)C)C(C)C |
InChiKey | ZNVBEWJRWHNZMK-AHWIEGLVSA-N |
Calcineurin inhibitor. Potent inhibitor of tumor promoting phorbol ester (TPA/PMA) effects.