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Cypermethrin

(HB0222)
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Product overview

Name Cypermethrin
Purity >96%
Description Potent PP2B inhibitor
Biological Data Solubility & Handling Chemical Data Related Areas Calculators Technical guides (1) Reviews References (4)
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Biological Data

Biological description Potent phosphatase 2B (PP2B) inhibitor (IC50 = 40 pM). Type II synthetic pyrethroid insecticide. Interacts with sodium channels producing neurotoxin effects. Also potent calcineurin inhibitor (IC50 = 100 nM). Blood brain barrier permeable.

Solubility & Handling

Solubility overview Soluble in ethanol (25mg/ml) or DMSO
Storage instructions +4°C
Storage of solutions Prepare and use solutions on the same day if possible. Store solutions at -20°C for up to one month if storage is required. Equilibrate to RT and ensure the solution is precipitate free before use.
Shipping Conditions Stable for ambient temperature shipping. Follow storage instructions on receipt.
Important This product is for RESEARCH USE ONLY and is not intended for therapeutic or diagnostic use. Not for human or veterinary use.

Calculators

Molarity

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More Info

Dilution

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Chemical Data

Purity >96%
Molecular Weight 416.3
Chemical structure Cypermethrin [52315-07-8] Chemical Structure
Molecular Formula C22H19Cl2NO3
CAS Number 52315-07-8
PubChem identifier 2912
SMILES CC1(C)C(\C=C(/Cl)Cl)C1C(=O)OC(C#N)C1=CC(OC2=CC=CC=C2)=CC=C1

References for Cypermethrin

References are publications that support the biological activity of the product

  • Effect of cypermethrin on memory, movement activity and coordination in mice after transient incomplete cerebral ischemia.

    Nieradko-Iwanicka B et al (2008) Pharmacol Rep 60(5) : 699-705.
    Read more (PubMedID: 19066417)

  • Inhibition of phosphatase 2B prevents expression of hippocampal long-term potentiation.

    Wang JH et al (1994) Neuroreport 5(17) : 2377-80.
    Read more (PubMedID: 7881062)

  • Specific inhibition of calcineurin by type II synthetic pyrethroid insecticides.

    Enan E et al (1992) Biochem Pharmacol 43(8) : 1777-84.
    Read more (PubMedID: 1315545)

  • Specific inhibition of calcineurin by type II synthetic pyrethroid insecticides.

    Enan E et al (1992) Biochem Pharmacol 43(8) : 1777-84.
    Read more (PubMedID: 1315545)

4 Item(s)

Grouped product items
Order: HB0222
Pack PriceQty
1g
$595
Potent PP2B inhibitor
Shipping Info

Standard: $35

Hazardous: $35

Shipped on ice: $35

Shipping will be calculated at checkout

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