Transporters
Transporters are integral transmembrane proteins involved in the movement of ions, small molecules, peptides, lipids or macromolecules, such as another protein, across a biological membrane. The energy required for active transport processes is obtained by hyrdolyzing ATP or by utilising ion gradients. The three major classes of ATP-driven transporters are: P-type ATPases (eg. Ca2+-ATPases and Na+,K+-ATPases); F-type or V-type ATPases and ATP-binding cassette transporters. The solute carrier family of transporters include the biogenic amine transporters (NET, DAT and SERT) the Na+/H+ exchanger, glutamate transporters (EAAT) and GABA transporters (GAT). Researchers can save up to 50% on transporter blockers and inhibitors from Hello Bio – they are up to half the price of other suppliers and have been reviewed and cited by researchers worldwide.
View transporter products: Cannabinoid | Dopamine | GABA | Glutamate | Glycine | Monoamine | Multidrug Transporter | Na+ / Ca2+ exchangers | Na+ / H+ exchangers | Norepinephrine | Serotonin (5-HT)
IWP 4 (HB3066)
Description:Potent Wnt/β-catenin signaling inhibitor. Induces cardiomyocyte differentiation of hESCs and iPSCs.
Purity:>98%
Jasplakinolide (HB3946)
Description:Cell permeable, non-fluorescent F-actin probe. Induces actin polymerization and stabilization.
Purity:>98%
JC-1 (HB0791)
Description:Mitochondrial membrane potential indicator/dye. Widely used in apoptosis studies.
Purity:>95%
JK 184 (HB3179)
Description:Downstream Hedgehog signaling pathway inhibitor. Alcohol dehydrogenase 7 inhibitor.
Purity:>99%
Kainic acid (HB0355)
Description:Prototypic, selective kainate receptor agonist. Potent excitant and neurotoxin.
Purity:>98%
Kenpaullone (HB1266)
Description:Potent CDK inhibitor. Also GSK-3 inhibitor. Generates iPSCs.
Purity:>98%