Nuclear Receptors
Nuclear hormone receptors (nuclear receptors) are specialised transcription factors which bind to specific sequences of DNA of particular target genes. They regulate transcription of these target genes in response to a variety of endogenous ligands. Nuclear receptors are classified into two major subfamilies: steroid and non-steroid hormone receptors. Steroid hormone receptors include receptors for estrogen (ER), androgen, glucocorticoid, mineralocorticoid and progesterone. Examples of non-steroid hormone receptors include thyroid receptors, retinoic acid receptors and peroxisome proliferator-activated receptors (PPAR). Researchers can save up to 50% on nuclear hormone receptor agonists, antagonists and modulators from Hello Bio - they are up to half the price of other suppliers.
- Description:
Antibody to VGAT - GABA transporter and GABAergic neuron marker. Part of the ValidAb™ range of highly validated, data-rich antibodies.
Host: RabbitClonality: PolyclonalReactivity Tested: Mouse, Rat Vigabatrin (HB0868)
Description:Selective, irreversible GABA-T (transaminase) inhibitor
Purity:>98%
Anti-Vimentin antibody ValidAbâ„¢ (HB6497)
Description:Monoclonal antibody to Vimentin - class III intermediate filament expressed in mesenchymal cells used as a marker of epithelial-mesenchymal transition. Part of the ValidAbâ„¢ range of highly validated, data-rich antibodies.Â
Host: MouseClonality: MonoclonalReactivity Tested: Rat, Human, Mouse (no staining)Anti-Vimentin antibody ValidAbâ„¢ (HB7843)
Description:Antibody to Vimentin - class III intermediate filament expressed in mesenchymal cells used as a marker of epithelial-mesenchymal transition. Part of the ValidAbâ„¢ range of highly validated, data-rich antibodies.Â
Host: GoatClonality: PolyclonalReactivity Tested: Rat, HumanAnti-BrdU antibody ValidAbTM (HB9919)
Description:Antibody to BrdU - thymidine analogue incorporated into DNA during replication therefore used as a marker of proliferating cells. Part of the ValidAbâ„¢ range of highly validated, data-rich antibodies.Â
Host: MouseClonality: MonoclonalReactivity Tested: NAVU 0357017 hydrochloride (HB1498)
Description:Potent, selective M1 receptor allosteric agonist
Purity:>98%