Nuclear Receptors
Nuclear hormone receptors (nuclear receptors) are specialised transcription factors which bind to specific sequences of DNA of particular target genes. They regulate transcription of these target genes in response to a variety of endogenous ligands. Nuclear receptors are classified into two major subfamilies: steroid and non-steroid hormone receptors. Steroid hormone receptors include receptors for estrogen (ER), androgen, glucocorticoid, mineralocorticoid and progesterone. Examples of non-steroid hormone receptors include thyroid receptors, retinoic acid receptors and peroxisome proliferator-activated receptors (PPAR). Researchers can save up to 50% on nuclear hormone receptor agonists, antagonists and modulators from Hello Bio - they are up to half the price of other suppliers.
Anisomycin (HB2239)
Description:Protein synthesis inhibitor. Potent JNK / p38 MAPK activator.
Purity:>98%
- Description:
Identifies early apoptotic, necrotic and viable cells
- Description:
Detects apoptosis by staining phosphatidylserine molecules translocated to the outside of the cell membrane.
Antibody penetration buffer (HB9812)
Description:Helps primary and secondary antibodies penetrate the cells of tissue or 3D cell culture when performing immunohistochemistry (IHC) or immuno-labeling
L-AP4 (HB0370)
Description:L-AP4 is a selective group III mGluR agonist which inhibits synaptic transmission.
Purity:>99%
DL-AP4 Sodium salt (HB0250)
Description:Water soluble form of DL-AP4, non-selective glutamate antagonist
Purity:>99%
D-AP5 (HB0225)
Description:Selective, competitive NMDA receptor antagonist. Inhibits NMDAR-synaptic plasticity.
Purity:>99%