Mineralocorticoid

Selective leukotriene LTD4 receptor antagonist. Potent MRP1 inhibitor.

Selective K_v7.2 / K_v7.4 channel activator

Selective mGlu₃ negative allosteric modulator

Selective K_2P2.1 (TREK-1) and K_2P10.1 (TREK-2) activator

Covalent K_2P2.1 (TREK-1) modulator

Selective K_2P2.1 (TREK-1) and K_2P10.1 (TREK-2) activator

Caged glutamate that rapidly and efficiently releases glutamate when photolysed

Newly identified, highly selective FFA2-DREADD agonist

NLRP3/NALP3 inflammasome activator

5-HT₄ receptor agonist. Also 5-HT₃ antagonist.