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Group I (mGlu5, mGlu1)
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Group I metabotropic glutamate receptors (mGlu1, mGlu5) are coupled with phospholipase C (PLC) via Gq proteins; activation causes increased levels of IP3 and diacylglycerol, with intracellullar Ca2+ release and protein kinase C (PKC) activation. Group I receptors are predominantly located post synaptically. Researchers can save 50% on group I metabotropic glutamate receptor agonists, antagonists, positive allosteric modulators (PAMs) and negative allosteric modulators (NAMs) from Hello Bio - they are up to half the price of other suppliers.
8-Bromo-cAMP sodium salt (8-Br-cAMP) (HB0090)
Description:Cell permeable PKA activator
Purity:>99%
Bromocriptine mesylate (HB1813)
Description:Potent, selective D2-like receptor agonist
Purity:>98%
CAT335 (HB8146)
Description:K2P2.1 (TREK-1) modulator. Selectively and irreversibly activates TREK-1CG* but not wild-type K2P2.1 (TREK-1)
Purity:>98%