8-Bromo-cAMP sodium salt (8-Br-cAMP) product vial image | Hello Bio
8-Bromo-cAMP sodium salt (8-Br-cAMP) product vial image | Hello Bio
Biological Data
Biological description
Cell-permeable protein kinase A (PKA) activator. cAMP analog which has increased metabolic stability and membrane permeability compared with cAMP. Activates cAMP-dependent protein kinase with long-acting effects due to its resistance to cAMP phosphodiesterase (PDE).
Enhances the induction of pluripotency in human fibroblast cells by improving the reprogramming efficiency of human neonatal foreskin fibroblast (HFF1) cells in combination with VPA (valproic acid).
In combination with IBMX, also promotes the differentiation of human iPS cell–derived intestinal epithelial cells
Solubility & Handling
Solubility overview
Soluble in water (100mM)
Storage instructions
-20°C (desiccate)
Storage of solutions
Prepare and use solutions on the same day if possible. Store solutions at -20°C for up to one month if storage is required. Equilibrate to RT and ensure the solution is precipitate free before use.
Shipping Conditions
Stable for ambient temperature shipping. Follow storage instructions on receipt.
Important
This product is for RESEARCH USE ONLY and is not intended for therapeutic or diagnostic use. Not for human or veterinary use.
Y-27632 is a selective ROCK inhibitor. Frequently used 3D growth matrix component and for production of organoids. Also used when inducing neurons from fibroblasts. Manufactured to a high degree of optical purity.
Understanding purity and quality - a guide for life scientists
