Group I (mGlu5, mGlu1)
Group I metabotropic glutamate receptors (mGlu1, mGlu5) are coupled with phospholipase C (PLC) via Gq proteins; activation causes increased levels of IP3 and diacylglycerol, with intracellullar Ca2+ release and protein kinase C (PKC) activation. Group I receptors are predominantly located post synaptically. Researchers can save 50% on group I metabotropic glutamate receptor agonists, antagonists, positive allosteric modulators (PAMs) and negative allosteric modulators (NAMs) from Hello Bio - they are up to half the price of other suppliers.
Territrem B (HB4104)
Description:Potent, specific, irreversible acetylcholinesterase (AChE) inhibitor.
Purity:>95%
Tetrabenazine (HB1711)
Description:Potent inhibitor of vesicular monoamine transport; depletes 5-HT stores
Purity:>98%
Tetrodotoxin (citrate free) (HB1034)
Description:Potent, selective, use-dependent Na+ channel blocker. Citrate free.
Purity:>99%
Tetrodotoxin citrate (HB1035)
Description:Potent, selective, use-dependent Na+ channel blocker. Citrate Salt.
Purity:>99%