DREADD

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Designer receptors exclusively activated by designer drugs (DREADDs) are genetically engineered GPCRs that are activated by physiologically inert synthetic small molecules (designer drugs) but not their endogenous ligand. Read our DREADDs mini-review or for practical advice on using these ligands in the lab see Stability of Water-Soluble DREADD Ligands in Solution: A Technical Review and Clozapine N-Oxide (freebase) - a technical review on stability, solubility and use in the lab).

Items 311-320 of 747

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  1. Pack:
    2mg
    Price:
    $143
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    Pack:
    5mg
    Price:
    $196
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    Pack:
    10mg
    Price:
    $341
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    Pack:
    50mg
    Price:
    $1,093
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  2. Description:

    Endogenous HDAC1, HDAC3 and HDAC4 inhibitor

    Purity:

    >98%

    Pack:
    25mg
    Price:
    $54
    Qty:
    Pack:
    100mg
    Price:
    $118
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  3. Description:

    Endogenous HDAC1, HDAC3 and HDAC4 inhibitor

    Purity:

    >98%

    Pack:
    25mg
    Price:
    $48
    Qty:
    Pack:
    100mg
    Price:
    $109
    Qty:
  4. Description:

    Synthetic estrogen receptor ligand. Widely used in genome engineering (e.g. CreER/ CRISPR-Cas9).

    Purity:

    >98%

    Pack:
    10mg
    Price:
    $47
    Qty:
    Pack:
    50mg
    Price:
    $183
    Qty:
  5. 17  Reviews
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    Description:

    Estrogen receptor ligand. For inducible genome manipulation (e.g. Cre-LoxP (CreER)/ TRAP/ CRISPR-Cas9).

    Purity:

    >98%

    Pack:
    10mg
    Price:
    $69
    Qty:
    Pack:
    50mg
    Price:
    $239
    Qty:
  6. Description:

    Specific and irreversible HMG-CoA synthase inhibitor

    Purity:

    >95%

    Pack:
    500μg
    Price:
    $210
    Qty:
    Pack:
    1mg
    Price:
    $372
    Qty:
  7. Description:

    Pan kinase inhibitor. Potently inhibits MEK1, Cdk1, Cdk2, Cdk3 and Cdk5 and GSK-3β.

    Purity:

    >97%

    Pack:
    250μg
    Price:
    $201
    Qty:
    Pack:
    1mg
    Price:
    $669
    Qty:
  8. Pack:
    100μg
    Price:
    $243
    Qty:
  9. Description:

    BET bromodomain inhibitor, also promotes differentiation of hiPSCs into megakaryocytes

    Purity:

    >98%

    Pack:
    50mg
    Price:
    $1,242
    Qty:
  10. IBMX (HB3000)

    Description:

    Non-selective, competitive cAMP and cGMP PDE inhibitor. Facilitates neural progenitor cell differentiation.

    Purity:

    >98%

    Pack:
    100mg
    Price:
    Qty:
    Pack:
    500mg
    Price:
    $134
    Qty:
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