DREADD
Designer receptors exclusively activated by designer drugs (DREADDs) are genetically engineered GPCRs that are activated by physiologically inert synthetic small molecules (designer drugs) but not their endogenous ligand. Read our DREADDs mini-review or for practical advice on using these ligands in the lab see Stability of Water-Soluble DREADD Ligands in Solution: A Technical Review and Clozapine N-Oxide (freebase) - a technical review on stability, solubility and use in the lab).
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SAG (HB3107)
Description:Cell permeable Sonic hedgehog (Shh) agonist and Smo agonist. Enhances neuronal differentiation of iPSC into dopaminergic neurons.
Purity:>98%
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SAG Analog (highly active) (HB4070)
Description:Highly active Sonic hedgehog agonist. Also smoothened (Smo) agonist.
Purity:>98%
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SAG Analog (LowTox) (HB4071)
Description:Low toxicity Sonic hedgehog agonist. Also smoothened (Smo) agonist.
Purity:>98%
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