DREADD
Designer receptors exclusively activated by designer drugs (DREADDs) are genetically engineered GPCRs that are activated by physiologically inert synthetic small molecules (designer drugs) but not their endogenous ligand. Read our DREADDs mini-review or for practical advice on using these ligands in the lab see Stability of Water-Soluble DREADD Ligands in Solution: A Technical Review and Clozapine N-Oxide (freebase) - a technical review on stability, solubility and use in the lab).
- Description:
Effective agonist for muscarinic-based DREADDs in vitro and in vivo. Non-CNO chemogenetic actuator. Water soluble.
Purity:>98%
-
Prochlorperazine dimaleate (HB1907)
Description:D2 receptor antagonist. Also 5-HT3 and nAChR antagonist.
Purity:>99%
-
Quetiapine hemifumarate (HB1803)
Description:5-HT2 and D2 antagonist. Atypical antipsychotic.
Purity:>99%
-
-
Ranitidine hydrochloride (HB2630)
Description:Potent, selective, competitive H2 receptor antagonist
Purity:>99%
- Description:
mGlu5 negative allosteric modulator
Purity:>98%
-
Riluzole hydrochloride (HB0548)
Description:Na+ channel blocker / glutamate inhibitor. TREK-1 K2P channel activator. Water soluble.
Purity:>98%
-
