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Designer receptors exclusively activated by designer drugs (DREADDs) are genetically engineered GPCRs that are activated by physiologically inert synthetic small molecules (designer drugs) but not their endogenous ligand. Read our DREADDs mini-review or for practical advice on using these ligands in the lab see Stability of Water-Soluble DREADD Ligands in Solution: A Technical Review and Clozapine N-Oxide (freebase) - a technical review on stability, solubility and use in the lab).
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Sericic acid (HB4081)
Description:Phosphodiesterase 4 (PDE4) inhibitor with various biological actions
Purity:>95%
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Sertraline hydrochloride (HB1717)
Description:Potent, selective 5-HT re-uptake inhibitor (SSRI)
Purity:>98%
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SKF 83566 hydrobromide (HB1863)
Description:Potent, selective D1-like receptor antagonist
Purity:>98%
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SKF 89976A hydrochloride (HB0976)
Description:Potent, selective, competitive GAT-1 GABA uptake inhibitor
Purity:>99%
