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Biological Data
| Biological description | Potent and competitive NOS inhibitor (Ki = 5.2 nM for mouse iNOS). |
Solubility & Handling
| Solubility overview | Soluble in DMSO or water |
| Important | This product is for RESEARCH USE ONLY and is not intended for therapeutic or diagnostic use. Not for human or veterinary use. |
Chemical Data
| PubChem identifier | 9813062 |
References for S-Isopropyl-ITU hydrobromide
References are publications that support the biological activity of the product
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Mapping the active site polarity in structures of endothelial nitric oxide synthase heme domain complexed with isothioureas.
Li H et al (2000) J Inorg Biochem 81(3) : 133-9. -
Isothioureas: potent inhibitors of nitric oxide synthases with variable isoform selectivity.
Southan GJ et al (1995) Br J Pharmacol 114(2) : 510-6. -
Potent and selective inhibition of human nitric oxide synthases. Inhibition by non-amino acid isothioureas.
Garvey EP et al (1994) J Biol Chem 269(43) : 26669-76.
Potent, competitive NOS inhibitor
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