G protein coupled receptors
G-protein-coupled receptors (also known as GPCRs, transmembrane receptors, or 7-TM receptors), are integral membrane proteins that contain seven membrane-spanning domains (helices). They are coupled to heterotrimeric G proteins on the intracellular side of the cell membrane. Ligand binding causes a conformational change in the GPCR, that is then transmitted to the G protein, activating a signal transduction pathway. Researchers can save up to 50% on GPCR receptor agonists, antagonists and allosteric modulators from Hello Bio - they are up to half the price of other suppliers.
View products: ACh Muscarinic | Adrenoceptors | Adenosine | Cannabinoid | Dopamine | GABAB | Histamine | Metabotropic Glutamate Receptors | Opioid | Peptide Receptors | Purinergic P2Y | Serotonin (5HT) | Neuroscience Research Tools
Go 6983 (HB0303)
Description:Broad spectrum PKC inhibitor. Optimizes naïve human pluripotent stem cell growth and viability
Purity:>98%
H 89 dihydrochloride (HB0314)
Description:Potent, non-selective kinase inhibitor.Also improves dissociate hESCs survival and clonogenicity.
Purity:>99%
I-BET 151 hydrochloride (HB1446)
Description:BET bromodomain inhibitor, also promotes differentiation of hiPSCs into megakaryocytes
Purity:>98%
IBMX (HB3000)
Description:Non-selective, competitive cAMP and cGMP PDE inhibitor. Facilitates neural progenitor cell differentiation.
Purity:>98%
IQ 1 (HB3282)
Description:Wnt pathway activator. Maintains ESC pluripotency in Wnt3a treated cells.
Purity:>99%
ISX 9 (HB3401)
Description:Neurogenic agent. Induces SVZ progenitor neuronal differentiation and cardiomyogenic differentiation.
Purity:>99%
ITD 1 (HB3446)
Description:Selective TGF-β signaling inhibitor. Induces cardiomyocyte differentiation in ESCs.
Purity:>98%
IWP 2 (HB0344)
Description:Potent Wnt pathway inhibitor and PORCN inhibitor. Suppresses R1 ESC self-renewal. Used in the production of cardiac organoids.
Purity:>98%