G protein coupled receptors
G-protein-coupled receptors (also known as GPCRs, transmembrane receptors, or 7-TM receptors), are integral membrane proteins that contain seven membrane-spanning domains (helices). They are coupled to heterotrimeric G proteins on the intracellular side of the cell membrane. Ligand binding causes a conformational change in the GPCR, that is then transmitted to the G protein, activating a signal transduction pathway. Researchers can save up to 50% on GPCR receptor agonists, antagonists and allosteric modulators from Hello Bio - they are up to half the price of other suppliers.
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Sericic acid (HB4081)
Description:Phosphodiesterase 4 (PDE4) inhibitor with various biological actions
Purity:>95%
Sertraline hydrochloride (HB1717)
Description:Potent, selective 5-HT re-uptake inhibitor (SSRI)
Purity:>98%
SKF 83566 hydrobromide (HB1863)
Description:Potent, selective D1-like receptor antagonist
Purity:>98%
SKF 89976A hydrochloride (HB0976)
Description:Potent, selective, competitive GAT-1 GABA uptake inhibitor
Purity:>99%