G protein coupled receptors
G-protein-coupled receptors (also known as GPCRs, transmembrane receptors, or 7-TM receptors), are integral membrane proteins that contain seven membrane-spanning domains (helices). They are coupled to heterotrimeric G proteins on the intracellular side of the cell membrane. Ligand binding causes a conformational change in the GPCR, that is then transmitted to the G protein, activating a signal transduction pathway. Researchers can save up to 50% on GPCR receptor agonists, antagonists and allosteric modulators from Hello Bio - they are up to half the price of other suppliers.
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Alprenolol hydrochloride (HB1734)
Description:Non-selective β-adrenoceptor antagonist. Also a 5-HT1A receptor antagonist.
Purity:>99%
Alsterpaullone (HB3754)
Description:Potent CDK1 inhibitor. Also shows activity at GSK-3β
Purity:>98%
Altenusin (HB3755)
Description:Non-competitive, specific neutral sphingomyelinase (N-SMase) inhibitor.
Purity:>97%
AM251 (HB2776)
Description:Potent, selective CB1 receptor antagonist / inverse agonist
Purity:>98%
AM281 (HB2312)
Description:Potent, selective CB1 receptor antagonist / inverse agonist
Purity:>98%
AM 404 (HB1174)
Description:Selective, competitive carrier-mediated anandamide transport inhibitor
Purity:>98%
Amantadine hydrochloride (HB0109)
Description:Non-competitive NMDA receptor antagonist
Purity:>98%
Amastatin hydrochloride (HB3757)
Description:Competitive aminopeptidase (AP) inhibitor
Purity:>98%