G protein coupled receptors
G-protein-coupled receptors (also known as GPCRs, transmembrane receptors, or 7-TM receptors), are integral membrane proteins that contain seven membrane-spanning domains (helices). They are coupled to heterotrimeric G proteins on the intracellular side of the cell membrane. Ligand binding causes a conformational change in the GPCR, that is then transmitted to the G protein, activating a signal transduction pathway. Researchers can save up to 50% on GPCR receptor agonists, antagonists and allosteric modulators from Hello Bio - they are up to half the price of other suppliers.
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Carboplatin (HB3824)
Description:Cisplatin analog. Blocks DNA replication and transcription.
Purity:>98%
(S)-4-Carboxyphenylglycine (HB0049)
Description:Competitive, selective group 1 mGlu antagonist
Purity:>99%
CCG 1423 (HB3389)
Description:Rho/SRF pathway inhibitor. Induces intermediate mesoderm differentiation from ESCs.
Purity:>99%
Celastrol (HB4605)
Description:Anti-oxidant, anti-inflammatory compound with many actions. Topoisomerase II inhibitor.
Purity:>98%
Cesium Gluconate (Cs-Gluc) (HB4822)
Description:Potassium channel blocker. Component in cesium gluconate-based internal solutions used for patch clamp electrophysiology.