GluN2C

Potent TRPM8 channel agonist

Sustains ESC self-renewal and pluripotency

AMPA receptor positive allosteric modulator

Competitive, selective, GluA2 (GluR2)-lacking AMPA receptor blocker

Non-competitive GluN2B subunit selective NMDAR allosteric inhibitor

Toll-like receptor 7 (TLR7) agonist

Synthetic PKC activator

Potent muscarinic acetylcholine receptor superagonist. Also binds the hM3R-miniG_q DREADD receptor.

Selective 5-HT_1A agonist

Wnt pathway activator. Maintains ESC pluripotency in Wnt3a treated cells.