HMG-CoA synthase

Small molecule RNA polymerase II inhibitor

Potent, selective 5-HT₃ antagonist

Irreversible calmodulin antagonist

Pancreatic, gastric and carboxylester lipase inhibitor

Selective Na⁺ / K⁺ ATPase inhibitor. Shows antiviral activity.

5-HT_2A and D₂ antagonist. Antipsychotic.

Rasfarnesyltransferase inhibitor

Potent, selective serotonin reuptake inhibitor. Selective GRK2 inhibitor.

Potent, reversible, selective K_Ca channel inhibitor. Also SERCA inhibitor.

Potent, selective HDAC8 inhibitor