Small molecule RNA polymerase II inhibitor. Also induces dose-dependent cytotoxicity (IC50 = 4.81 µM) and disrupts interaction of PKCι and cyclin-dependent protein kinase 9/cyclin T1 complex. Anticancer agent that induces apoptosis. Displays antiproliferative properties.
Solubility & Handling
Solubility overview
Soluble in DMSO (100mM) or ethanol (25mM)
Storage instructions
+4°C
Storage of solutions
Prepare and use solutions on the same day if possible. Store solutions at -20°C for up to one month if storage is required. Equilibrate to RT and ensure the solution is precipitate free before use.
Shipping Conditions
Stable for ambient temperature shipping. Follow storage instructions on receipt.
Important
This product is for RESEARCH USE ONLY and is not intended for therapeutic or diagnostic use. Not for human or veterinary use.
![Oncrasin 1 [75629-57-1] Chemical Structure](https://cdn.hellobio.com/media/catalog/product//h/b/hb0473.png "Oncrasin 1 [75629-57-1]")
Understanding purity and quality - a guide for life scientists