Irreversible calmodulin antagonist that reacts with lysine residues (IC50 0.87-3.7 µM). Also inhibits calcium-dependent human growth hormone (hGH) release (approx Ki = 10 µM). A membrane permeable fungal metabolite and a phytotoxin. Displays antitumor and apoptotic inducing properties.
Solubility & Handling
Solubility overview
Soluble in DMSO or DMF
Important
This product is for RESEARCH USE ONLY and is not intended for therapeutic or diagnostic use. Not for human or veterinary use.
References are publications that support the biological activity of the product
Ophiobolin A, a sesterterpenoid fungal phytotoxin, displays higher in vitro growth-inhibitory effects in mammalian than in plant cells and displays in vivo antitumor activity.
![Ophiobolin A [988837] Chemical Structure](https://hellobio.com/media/catalog/product//h/b/hb0474.png "Ophiobolin A [988837]")
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