Broad

Abundant free amino acid found in the brain.

Competitive EAAT blocker. Inhibits glutamate uptake.

Selective class I HDAC inhibitor

Potent, selective Na_v1.7 inhibitor

Potent, non-competitive GluN2A subunit selective NMDA receptor antagonist

Potent and selective orexin OX₂ antagonist

5-HT₄ partial agonist

K_ir2.3 channel agonist

Acyl-CoA cholesterol acyltransferase 1 and 2 inhibitor

Antibacterial phytotoxin