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TC-N 1752

(HB1033)
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Product overview

Name TC-N 1752
Alternative names Compound 52
Purity >99%
Description Potent, selective Nav1.7 inhibitor
Biological Data Solubility & Handling Chemical Data Related Areas Calculators Technical guides (1) Reviews References (1) Frequently bought together
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Images

TC-N 1752 product vial image | Hello Bio
TC-N 1752 product vial image | Hello Bio

TC-N 1752 product vial image | Hello Bio

TC-N 1752 product vial image | Hello Bio

Biological Data

Biological description Potent and selective Nav1.7 channel inhibitor (IC50 = 0.17 µM). Shows antinociceptive actions.

Solubility & Handling

Solubility overview Soluble in DMSO (100mM) or HCl (10mM, 1eq HCl)
Storage instructions +4°C
Storage of solutions Prepare and use solutions on the same day if possible. Store solutions at -20°C for up to one month if storage is required. Equilibrate to RT and ensure the solution is precipitate free before use.
Shipping Conditions Stable for ambient temperature shipping. Follow storage instructions on receipt.
Important This product is for RESEARCH USE ONLY and is not intended for therapeutic or diagnostic use. Not for human or veterinary use.

Calculators

Molarity

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Dilution

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Chemical Data

Purity >99%
Chemical name N-[2-Methyl-3-[[4-[4-[[4-(trifluoro methoxy)phenyl]methoxy]-1-piperidinyl]-1,3,5-triaz in-2-yl]amino]phenyl]acetamide
Molecular Weight 516.52
Chemical structure TC-N 1752 [1211866-85-1] Chemical Structure
Molecular Formula C25H27F3N6O3
CAS Number 1211866-85-1
PubChem identifier 53361524
SMILES CC(C(NC(C)=O)=CC=C4)=C4NC1=NC=NC(N2CCC(OCC3=CC=C(OC(F)(F)F)C=C3)CC2)=N1
InChiKey QLKAFHZJICDACE-UHFFFAOYSA-N

References for TC-N 1752

References are publications that support the biological activity of the product

  • Identification of a potent, state-dependent inhibitor of Nav1.7 with oral efficacy in the formalin model of persistent pain.

    Bregman H et al (2011) J Med Chem 54(13) : 4427-45.
    Read more (PubMedID: 21634377)

1 Item

Grouped product items
Order: HB1033
Pack PriceQty
10mg
$224
50mg
$880
Potent, selective Nav1.7 inhibitor
Shipping Info

Standard: $35

Hazardous: $35

Shipped on ice: $35

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